Rabbit IgG Isotype Control

IgG is a monomeric immunoglobulin, built of two heavy chains gamma and two light chains. Each molecule has two antigen binding sites. This is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75% of serum immunoglobulins in humans. This is the only isotype that can pass through the human placenta, thereby providing protection to the fetus in its first weeks of life before its own immune system has developed. It can bind to many kinds of pathogens, for example viruses, bacteria, and fungi, and protects the body against them by complement activation (classic pathway), opsonization for phagocytosis and neutralisation of their toxins. There are 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Isotype Controls are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Rat, Rabbit.

We have publications tested in 5 applications: Flow-CS, ICC/IF, IF/IHC, In vitro, WB.

Showing Publications 1 - 10 of 10.

Publications using NBP2-24893	Applications	Species
Eustace NJ, Anderson JC, Langford CP et al. Myristoylated alanine-rich C-kinase substrate effector domain phosphorylation regulates the growth and radiation sensitization of glioblastoma. Int J Oncol. 2019-03-29 [PMID: 30942445] (WB, Rabbit) Details: Citation using the Azide Free form of this antibody.	WB	Rabbit
Vazquez Rodriguez G, Abrahamsson A, Jensen LDE et al. Adipocytes Promote Early Steps of Breast Cancer Cell Dissemination via Interleukin-8 Front. Immunol 2018-07-30 [PMID: 30105032] (ICC/IF, Human) Details: This citation used the Azide and BSA Free version of this antibody.	ICC/IF	Human
Freund A, Zhong Fl, Venteicher As et al. Proteostatic Control of Telomerase Function through TRiC-Mediated Folding of TCAB1. Cell. [PMID: 25467444] (In vitro) Details: Citation using the Azide Free form of this antibody.	In vitro
Shimazu T, Villena J, Tohno M et al. Immunobiotic Lactobacillus jensenii elicits anti-inflammatory activity in porcine intestinal epithelial cells by modulating negative regulators of the Toll-like receptor signaling pathway. Infect Immun. 2012-01-01 [PMID: 22083706] (Flow-CS) Details: Cat no 20304E (normal rabbit IgG isotype control): Flow (cell surface), Fig 4C (porcine intestinal epitheliocyte cell line).	Flow-CS
Chiba Eriko, Villena Julio, Hosoya Shoichi et al. A newly established bovine intestinal epithelial cell line is effective for in vitro screening of potential antiviral immunobiotic microorganisms for cattle. Res Vet Sci. [PMID: 22047818] (ICC/IF) Details: Citation using the Azide Free form of this antibody.	ICC/IF
Hosoya Shoichi, Villena Julio, Shimazu Tomoyuki et al. Immunobiotic lactic acid bacteria beneficially regulate immune response triggered by poly(I:C) in porcine intestinal epithelial cells. Vet Res. [PMID: 22046952] (IF/IHC) Details: Citation using the Azide Free form of this antibody.	IF/IHC
Liebelt B, Papapetrou P, Ali A et al. Exercise preconditioning reduces neuronal apoptosis in stroke by up-regulating heat shock protein-70 (heat shock protein-72) and extracellular-signal-regulated-kinase 1/2. Neuroscience. [PMID: 20083167] (Rat) Details: Citation using the Azide Free form of this antibody.		Rat
Wu J, Meng Z, Jiang M et al. Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific. Immunology. [PMID: 19922426] Details: Citation using the PE/Cy5 form of this antibody.
Patole PS, Pawar RD, Lech M et al. Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice. Nephrol Dial Transplant. 2006-11-01 [PMID: 16954173] Details: For IHC (frozen) on mouse kidney sections (Fig. 5): TLR3 (IMG-516), TLR7 (IMG-581A), TLR9 (IMG-431) and Rabbit IgG isotype control antibody (20304). For Flow (Intacellular) and Flow (Cell surface) on J774 mouse macrophage-like cell line (Fig 6B): TLR7 (IMG-581A), TLR9 (IMG-431) and Rabbit IG isotype control antibody (20304).
Wang J, Zheng C, Zhai Y, et al. High-density lipoprotein modulates tumor-associated macrophage for chemoimmunotherapy of hepatocellular carcinoma Nano Today 2021-04-01

Images	Ratings	Applications	Species	Date	Details
Enlarge	4 reviewed by: Verified Customer	IP	Human	08/26/2014	View Summary Application Immunoprecipitation Sample Tested HEK293 cells treated with etoposide (5h) Species Human

Array NBP2-24893

• IgG Antibodies
• IgG ELISA Kits
• IgG Isotype Controls
• IgG Kit
• IgG Proteins
• IgG Antibodies
• IgG ELISAs