IgG Antibody (IG266)

IgG is a monomeric immunoglobulin, built of two heavy chains gamma and two light chains. Each molecule has two antigen binding sites. This is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75% of serum immunoglobulins in humans. This is the only isotype that can pass through the human placenta, thereby providing protection to the fetus in its first weeks of life before its own immune system has developed. It can bind to many kinds of pathogens, for example viruses, bacteria, and fungi, and protects the body against them by complement activation (classic pathway), opsonization for phagocytosis and neutralisation of their toxins. There are 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: ELISA, RIP, WB.

Showing Publications 1 - 3 of 3.

Publications using NBP2-34250	Applications	Species
Zhao L, Zang Q, Liang G, Yao X LncRNA CECR7 boosts hepatocellular carcinoma progression by recruiting RNA binding protein U2AF2 to enhance the stability of EXO1 mRNA Heliyon 2023-09-01 [PMID: 37809785] (RIP, Human)	RIP	Human
Dombrowski JG, Barateiro A, Peixoto EPM et al. Adverse pregnancy outcomes are associated with Plasmodium vivax malaria in a prospective cohort of women from the Brazilian Amazon PLoS Negl Trop Dis 2021-04-29 [PMID: 33914739] (ELISA) Details: Citation using the Azide and BSA Free format of this antibody.	ELISA
van den Hoogen P, de Jager SCA, Huibers MMH et al. Increased circulating IgG levels, myocardial immune cells and IgG deposits support a role for an immune response in pre- and end-stage heart failure J. Cell. Mol. Med. 2019-09-26 [PMID: 31557411] (WB, Human)	WB	Human

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Natalie Erdmann	ICC	Human	05/28/2019	View Summary Application Immunocytochemistry Sample Tested LP-1 (multiple myeloma) and H929 (multiple myeloma) Species Human Lot 3535-4P 190321 Comments Comments 1. Cells immersion-fixed in 2%PFA 10 minutes, wash PBS X 3 2. Permeabilized 0.5% Triton X-100 5 minutes; wash PBS X 3 3. Block 10% donkey serum 1 hour 4. 1/200 NBP2-34250 O/N @4oC; wash PBS X 3 5. 1/1000 donkey F(ab’)2 Alexa Fluor 647 anti-mouse IgG (H+L) 1 hour @room temp (Jackson #715-606-150); wash PBS X 3 6. Olympus/BIOVIEW Cy5 filter 600ms exposure

Array NBP2-34250

• IgG Antibodies
• IgG ELISA Kits
• IgG Isotype Controls
• IgG Kit
• IgG Proteins
• IgG Antibodies
• IgG ELISAs