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IFN-alpha/beta R1 Antibody (85228) [Phycoerythrin]

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U937 human histiocytic lymphoma cell line was stained with Mouse Anti-Human IFN-a/ beta R1 PE-conjugated Monoclonal Antibody (Catalog # FAB245P, filled histogram) or isotype control antibody (Catalog # IC002P, open ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
85228
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

Order Details

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IFN-alpha/beta R1 Antibody (85228) [Phycoerythrin] Summary

Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IFN-alpha / beta  R1
Lys28-Lys436
Accession # AAA52730
Specificity
Detects human IFN-alpha / beta R1 in direct ELISAs and Western blots. In direct ELISAs, does not cross-react with recombinant human (rh) IFN‑ gamma  R1, rhIFN-gamma R2, recombinant mouse IFN-alpha / beta  R2, rhIL-10 R beta , rhIL-10 R alpha , or rhIL-20 R beta .
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IFNAR1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB245P in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

Sold under license from Pestka Biomedical Laboratories, Inc. d/b/a PBL Interferon Source.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IFN-alpha/beta R1 Antibody (85228) [Phycoerythrin]

  • alpha-type antiviral protein
  • AVP
  • beta-type antiviral protein
  • CRF2-1
  • Cytokine receptor class-II member 1
  • Cytokine receptor family 2 member 1
  • human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC
  • IFN-alpha/beta R1
  • IFN-alpha/beta receptor 1
  • IFN-alpha-REC
  • IFNAR
  • IFNAR1
  • IFN-aR1
  • IFNBR
  • IFNbR1
  • IFN-bR1
  • IFN-R-1
  • interferon (alpha, beta and omega) receptor 1
  • interferon alpha/beta receptor 1
  • interferon-alpha/beta receptor alpha chain
  • interferon-beta receptor 1
  • Type I interferon receptor 1

Background

Type I interferons (IFN-alpha , IFN-beta , IFN-omega ) bind to the type I IFN receptor, also called the IFN alpha/beta receptor. This receptor is composed of two chains, IFN-alpha / beta R1 and R2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for IFN-alpha/beta R1 Antibody (FAB245P)(7)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: Flow Cytometry.


Filter By Application
Flow Cytometry
(5)
All Applications
Filter By Species
Human
(5)
Mouse
(1)
All Species
Showing Publications 1 - 7 of 7.
Publications using FAB245P Applications Species
Oltin-Tiberiu Pop, Anne Geng, Emilio Flint, Arjuna Singanayagam, Caner Ercan, Lucia Possamai et al. AXL Expression on Homeostatic Resident Liver Macrophages Is Reduced in Cirrhosis Following GAS6 Production by Hepatic Stellate Cells Cellular and Molecular Gastroenterology and Hepatology 3/31/2023 [PMID: 37004869]
Sampath Katakam, Santosh Anand, Patricia Martin, Nicolo Riggi, Ivan Stamenkovic Necrotic debris and STING exert therapeutically relevant effects on tumor cholesterol homeostasis Life Science Alliance 3/1/2022 [PMID: 34983824]
S Gupta, S Nakabo, LP Blanco, LJ O'Neil, G Wigerblad, RR Goel, P Mistry, K Jiang, C Carmona-Ri, DW Chan, X Wang, HL Pedersen, M Gadkari, KN Howe, F Naz, S Dell'Orso, SA Hasni, C Dempsey, A Buscetta, PA Frischmeye, P Kruszka, M Muenke, LM Franco, HW Sun, MJ Kaplan Sex differences in neutrophil biology modulate response to type I interferons and immunometabolism Proc. Natl. Acad. Sci. U.S.A., 2020-06-29;0(0):. 2020-06-29 [PMID: 32601182] (Flow Cytometry, Human) Flow Cytometry Human
PJ Metz, KA Ching, T Xie, P Delgado Cu, S Niessen, JH Tatlock, K Jensen-Per, BW Murray Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling Cell Rep, 2020-02-11;30(6):1935-1950.e8. 2020-02-11 [PMID: 32049022] (Flow Cytometry, Human) Flow Cytometry Human
Safe and effective treatment of experimental neuroblastoma and glioblastoma using systemically administered triple microRNA-detargeted oncolytic Semliki Forest virus Clin Cancer Res, 2016-09-16;0(0):. 2016-09-16 [PMID: 27637889] (Flow Cytometry, Human, Mouse) Flow Cytometry Human, Mouse
Badr G, Saad H, Waly H Type I interferon (IFN-alpha/beta) rescues B-lymphocytes from apoptosis via PI3Kdelta/Akt, Rho-A, NFkappaB and Bcl-2/Bcl(XL). Cell. Immunol., 2010-02-24;263(1):31-40. 2010-02-24 [PMID: 20231019] (Flow Cytometry, Human) Flow Cytometry Human
Cironi P, Swinburne IA, Silver PA Enhancement of cell type specificity by quantitative modulation of a chimeric ligand. J. Biol. Chem., 2008-01-29;283(13):8469-76. 2008-01-29 [PMID: 18230610] (Flow Cytometry, Human) Flow Cytometry Human

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Bioinformatics

Gene Symbol IFNAR1
Uniprot