Novus Biologicals products are now on bio-techne.com

Human Total Legumain DuoSet ELISA, 15 Plate

Images

 

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

Human Total Legumain DuoSet ELISA, 15 Plate Summary

Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
LGMN

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY4769.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Total Legumain DuoSet ELISA, 15 Plate

  • AEP
  • Asparaginyl Endopeptidase
  • cysteine protease 1
  • Legumain
  • LGMN
  • LGMN1
  • Protease, cysteine 1
  • protease, cysteine, 1 (legumain)
  • PRSC1EC 3.4.22.34

Background

Legumain is a lysosomal cysteine protease that plays a pivotal role in the endosomal/lysosomal degradation system. Legumain deficiency causes the accumulation of pro-Cathepsins B, H and L, another group of lysosomal cysteine proteases. Overexpression of Legumain in tumors is significant for invasion/metastasis. Also known as Asparaginyl Endopeptidase, it specifically cleaves peptide bonds with Asn or Asp at the P1 position.

Customers Who Viewed This Item Also Viewed...

NBP1-32870
Species: Hu
Applications: IHC, IHC-P, IP, KD, WB
NBP2-15104
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
AF5866
Species: Hu
Applications: IHC, WB
NBP2-44520
Species: Ca(-), Hu, Rt(-)
Applications: Flow-IC, Flow, ICC/IF, IF, IHC, IHC-P, MI, WB
AF965
Species: Mu
Applications: IHC, Neut, WB
AF952
Species: Hu
Applications: ELISA(Cap), ELISA(Det), ELISA(Sta), IHC, IP, WB
NBP2-92677
Species: Hu, Mu, Rt
Applications: WB
NBP1-81293
Species: Hu
Applications: ICC/IF, IHC, IHC-P, KD, WB
NB100-74635
Species: Hu
Applications: IHC, IHC-P, IP, WB (-)
NBP2-30949
Species: Hu
Applications: IHC, IHC-P
NBP1-97512
Species: Mu
Applications: ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
NBP1-62583
Species: Hu
Applications: WB
AF1286
Species: Hu
Applications: IHC, IP, Simple Western, WB
NBP1-84957
Species: Hu
Applications: IHC, IHC-P, WB
H00000518-P01
Species: Hu
Applications: ELISA, AP, PA, WB
AF2340
Species: Hu
Applications: CyTOF-ready, Flow, IP, WB
AF3749
Species: Hu
Applications: IHC, WB
NB100-616
Species: Hu, Mu, Md, Pm, Rt
Applications: ChIP, EM, Flow-IC, Flow, ICC/IF, IP, In vitro, KD, WB
NB120-6405
Species: Rt
Applications: B/N, CyTOF-ready, EM, ELISA, Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP
DY4769
Species: Hu
Applications: ELISA

Publications for Legumain/Asparaginyl Endopeptidase (DY4769)(5)

We have publications tested in 1 confirmed species: Human.


Filter By Application
All Applications
Filter By Species
Human
(5)
All Species
Showing Publications 1 - 5 of 5.
Publications using DY4769 Applications Species
AS Clees, V Stolp, B Häupl, DC Fuhrmann, F Wempe, M Seibert, S Weber, A Banning, R Tikkanen, R Williams, B Brüne, H Serve, F Schnütgen, I von Metzle, N Kurrle Identification of the Cysteine Protease Legumain as a Potential Chronic Hypoxia-Specific Multiple Myeloma Target Gene Cells, 2022-01-15;11(2):. 2022-01-15 [PMID: 35053409] (Human) Human
NN Lunde, MH Haugen, KB Bodin Lars, I Damgaard, SJ Pettersen, R Kasem, W Rut, M Drag, M Poreba, HT Johansen, R Solberg Glycosylation is important for legumain localization and processing to active forms but not for cystatin E/M inhibitory functions Biochimie, 2017-05-17;0(0):. 2017-05-17 [PMID: 28528272] (Human) Human
Y Cui, Q Li, H Li, Y Wang, H Wang, W Chen, S Zhang, J Cao, T Liu Asparaginyl endopeptidase improves the resistance of microtubule-targeting drugs in gastric cancer through IQGAP1 modulating the EGFR/JNK/ERK signaling pathway Onco Targets Ther, 2017-02-03;10(0):627-643. 2017-02-03 [PMID: 28223821] (Human) Human
A Dutta, DN Potier, MJ Walker, OJ Gray, C Parker, M Holland, AJ Williamson, A Pierce, RD Unwin, S Krishnan, V Saha, AD Whetton Development of a selected reaction monitoring mass spectrometry-based assay to detect asparaginyl endopeptidase activity in biological fluids Oncotarget, 2016-10-25;7(43):70822-70831. 2016-10-25 [PMID: 27683124] (Human) Human
Pitteri SJ, JeBailey L, Faca VM, Thorpe JD, Silva MA, Ireton RC, Horton MB, Wang H, Pruitt LC, Zhang Q, Cheng KH, Urban N, Hanash SM, Dinulescu DM Integrated proteomic analysis of human cancer cells and plasma from tumor bearing mice for ovarian cancer biomarker discovery. PLoS ONE, 2009-11-19;4(11):e7916. 2009-11-19 [PMID: 19936259] (Human) Human

Reviews for Legumain/Asparaginyl Endopeptidase (DY4769) (0)

There are no reviews for Legumain/Asparaginyl Endopeptidase (DY4769). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for Legumain/Asparaginyl Endopeptidase (DY4769) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional Legumain/Asparaginyl Endopeptidase Products

Blogs on Legumain/Asparaginyl Endopeptidase

There are no specific blogs for Legumain/Asparaginyl Endopeptidase, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Review this Product

Be the first to review our Human Total Legumain DuoSet ELISA, 15 Plate and receive a gift card or discount.

Bioinformatics

Gene Symbol LGMN