Human Serpin E1/PAI-1 DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 10 of 20. Show All 20 Publications. Collapse Publications.

Publications using DY1786	Applications	Species
Lengvenyte, A;Cognasse, F;Hamzeh-Cognasse, H;Sénèque, M;Strumila, R;Olié, E;Courtet, P; Baseline circulating biomarkers, their changes, and subsequent suicidal ideation and depression severity at 6 months: A prospective analysis in patients with mood disorders Psychoneuroendocrinology 2024-07-06 [PMID: 39003840] (Human)		Human
Oezel, L;Wohltmann, M;Gondorf, N;Wille, J;Güven, I;Windolf, J;Thelen, S;Jaekel, C;Grotheer, V; Dupuytren's Disease Is Mediated by Insufficient TGF-?1 Release and Degradation International journal of molecular sciences 2023-10-11 [PMID: 37894778] (Human)		Human
Ahenkorah, B;Sakyi, SA;Fondjo, LA;Helegbe, G;Owiredu, EW;Der, EM;Amoah, LE;Kusi, KA;Obiri, D;Amoani, B;Bimpong, S;Ofosu, W;Obirikorang, C;Odame, E;Larbie, C;Arthur-Johnson, P;Quaye, I;Ametefe, EM;Okai, BK;Anormah, R;Akorli, E;Simono Charadan, AM;Aboubacar, RM;Amesewu, E;Gyan, B; Evaluating circulating soluble markers of endothelial dysfunction and risk factors associated with PE: A multicentre longitudinal case control study in northern Ghana Heliyon 2023-09-01 [PMID: 37662780] (Human)		Human
H L?rincz, B Ratku, S Csiha, I Seres, Z Szabó, G Paragh, M Harangi, S Somodi Impaired Organokine Regulation in Non-Diabetic Obese Subjects: Halfway to the Cardiometabolic Danger Zone International Journal of Molecular Sciences, 2023-02-18;24(4):. 2023-02-18 [PMID: 36835525] (Human)		Human
YH Su, YZ Wu, DK Ann, JL Chen, CY Kuo Obesity promotes radioresistance through SERPINE1-mediated aggressiveness and DNA repair of triple-negative breast cancer Cell Death & Disease, 2023-01-21;14(1):53. 2023-01-21 [PMID: 36681663] (Human)		Human
S Kuriyama, T Yamada, A Matsuda, G Takahashi, T Iwai, K Takeda, K Ueda, T Miyasaka, Y Yokoyama, S Shinji, H Sonoda, R Ohta, K Yonaga, S Kanaka, H Yoshida Biomarkers for anti-vascular endothelial growth factor drugs Oncology Letters, 2022-11-07;24(6):463. 2022-11-07 [PMID: 36406183] (Human)		Human
S Mogren, F Berlin, L Eskilsson, N Van Der Bu, E Tufvesson, CK Andersson Mast Cell Proteases Promote Diverse Effects on the Plasminogen Activation System and Wound Healing in A549 Alveolar Epithelial Cells Cells, 2022-09-18;11(18):. 2022-09-18 [PMID: 36139491] (Human)		Human
J Villar, R Herrán-Mon, E González-H, M Prieto-Gon, A Ambrós, A Rodríguez-, A Muriel-Bom, R Solano, C Cuenca-Rub, A Vidal, C Flores, JM González-M, MI García-Lao, Genetics o Clinical and biological markers for predicting ARDS and outcome in septic patients Scientific Reports, 2021-11-22;11(1):22702. 2021-11-22 [PMID: 34811434] (Human)		Human
E Jover, L Matilla, M Garaikoetx, A Fernández-, P Muntendam, F Jaisser, P Rossignol, N López-Andr Beneficial Effects of Mineralocorticoid Receptor Pathway Blockade against Endothelial Inflammation Induced by SARS-CoV-2 Spike Protein Biomedicines, 2021-06-03;9(6):. 2021-06-03 [PMID: 34204890] (Human)		Human
MR Hadjichara, BT Roux, E Csomor, CA Feghali-Bo, LA Murray, DL Clarke, MA Lindsay Long intergenic non-coding RNAs regulate human lung fibroblast function: Implications for idiopathic pulmonary fibrosis Sci Rep, 2019-04-15;9(1):6020. 2019-04-15 [PMID: 30988425] (Human)		Human
RS Thwaites, NC Gunawardan, V Broich, EH Mann, J Ahnström, GA Campbell, S Lindsley, N Singh, T Tunstall, DA Lane, PJ Openshaw, CM Hawrylowic, TT Hansel Biphasic activation of complement and fibrinolysis during the human nasal allergic response J. Allergy Clin. Immunol., 2018-02-07;0(0):. 2018-02-07 [PMID: 29427640] (Human)		Human
M Ossorio, MA Bajo, G Del Peso, V Martínez, M Fernández, MJ Castro, A Rodríguez-, R Madero, T Bellón, R Selgas Sustained low peritoneal effluent CCL18 levels are associated with preservation of peritoneal membrane function in peritoneal dialysis PLoS ONE, 2017-04-17;12(4):e0175835. 2017-04-17 [PMID: 28414753] (Human)		Human
CA Valle Oseg, JV Spencer Human cytomegalovirus interleukin-10 enhances matrigel invasion of MDA-MB-231 breast cancer cells Cancer Cell Int, 2017-02-13;17(0):24. 2017-02-13 [PMID: 28228690] (Human)		Human
Serum from Varicose Patients Induces Senescence-Related Dysfunction of Vascular Endothelium Generating Local and Systemic Proinflammatory Conditions Oxid Med Cell Longev, 2016-11-23;2016(0):2069290. 2016-11-23 [PMID: 27994710] (Human)		Human
Aubin K, Safoine M, Proulx M, Audet-Casgrain M, Côté J, Tetu F, Roy A, Fradette J Characterization of In Vitro Engineered Human Adipose Tissues: Relevant Adipokine Secretion and Impact of TNF-alpha. PLoS ONE, 2015-09-14;10(9):e0137612. 2015-09-14 [PMID: 26367137] (Human)		Human
Tasev D, van Wijhe M, Weijers E, van Hinsbergh V, Koolwijk P Long-Term Expansion in Platelet Lysate Increases Growth of Peripheral Blood-Derived Endothelial-Colony Forming Cells and Their Growth Factor-Induced Sprouting Capacity. PLoS ONE, 2015-06-15;10(6):e0129935. 2015-06-15 [PMID: 26076450] (Human)		Human
Kim Aubin, Caroline Vincent, Maryse Proulx, Dominique Mayrand, Julie Fradette Creating capillary networks within human engineered tissues: Impact of adipocytes and their secretory products Acta Biomaterialia 2015-01-01 [PMID: 25278444] (Human)		Human
Ekstrom M, Liska J, Eriksson P, Sverremark-Ekstrom E, Tornvall P Stimulated in vivo synthesis of plasminogen activator inhibitor-1 in human adipose tissue. Thromb Haemost, 2012-06-28;108(3):485-92. 2012-06-28 [PMID: 22740034] (Human)		Human
Dunoyer-Geindre S, Fish RJ, Kruithof EK Regulation of the endothelial plasminogen activator system by fluvastatin. Role of Rho family proteins, actin polymerisation and p38 MAP kinase. Thromb. Haemost., 2010-12-21;105(3):461-72. 2010-12-21 [PMID: 21174002] (Human)		Human
Becker M, Szarvas T, Wittschier M, vom Dorp F, Totsch M, Schmid KW, Rubben H, Ergun S Prognostic impact of plasminogen activator inhibitor type 1 expression in bladder cancer. Cancer, 2010-10-01;116(19):4502-12. 2010-10-01 [PMID: 20564745] (Human)		Human
Show All 20 Publications. Collapse Publications.

Array DY1786

• Serpin E1/PAI-1 Antibodies
• Serpin E1/PAI-1 Antibody Pair
• Serpin E1/PAI-1 ELISA Kits
• Serpin E1/PAI-1 Lysate
• Serpin E1/PAI-1 Proteins
• Serpin E1/PAI-1 ELISAs
• Serpin E1/PAI-1 Proteins and Enzyme