Human Phospho-p70 S6 Kinase (T389) DuoSet IC ELISA, 2 Plate Summary
Source
N/A
Inter-Assay
Intra-Assay
Spike Recovery
Sample Volume
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Packaging, Storage & Formulations
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Human Phospho-p70 S6 Kinase (T389) DuoSet IC ELISA, 2 Plate
Background
p70 S6 kinase is a Ser/Thr kinase activated by such mitogens as EGF, IGF-I, and insulin. The S6 protein of the 40S ribosomal subunit is a major substrate of p70 S6 kinase, and its phosphorylation upregulates the translation of mRNAs containing an oligopyrimidine tract at their transcriptional start site. The activity of p70 S6 kinase is controlled by multiple phosphorylation events, with phosphorylation at T229 by PDK1 and T389 by mTOR most critical for kinase function.
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Publications for p70 S6 Kinase/S6K (DYC896B-2)(3)
We have publications tested in 2 confirmed species: Human, Mouse.
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Publications using DYC896B-2
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Y Jung, M Son, YR Nam, J Choi, JR Heath, S Yang Microfluidic Single-Cell Proteomics Assay Chip: Lung Cancer Cell Line Case Study Micromachines, 2021-09-23;12(10):. 2021-09-23 [PMID: 34683198] (Human)
Human
Neurotensin stimulates sortilin and mTOR in human microglia inhibitable by methoxyluteolin, a potential therapeutic target for autism Proc Natl Acad Sci USA, 2016-09-23;0(0):. 2016-09-23 [PMID: 27663735] (Human)
Human
Hashimoto T, Perlot T, Rehman A ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation. Nature, 2012-07-25;487(7408):477-81. 2012-07-25 [PMID: 22837003] (Mouse)
Mouse
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