Human Nidogen-1/Entactin DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Nidogen-2 (also called entactin-2) is a 200 kDa, secreted, basement membrane glycoprotein. Nidogens-1 and -2 are expressed in nearly all basement membranes where they interact with laminins, collagen type IV, and proteoglycan family members. Nidogen-2 contains three globular domains (G1-3) separated by a link region and an extended rod-shaped segment. The G1 domain is reported to bind type IV collagen, the G2 domain interacts with perlecan, and C-terminal G3 is associated with laminin binding. There is one EGF-like motif and a short peptide that ligates alpha 3 beta 1 integrins. The rod-shaped segment contains four additional EGF-like motifs and two thyroglobulin type 1 domains that serve as a binding site for alpha V beta 3 integrins.

We have publications tested in 1 confirmed species: Human.

Showing Publication 1 - 1 of 1.

Publication using DY2570	Applications	Species
N Willumsen, CL Bager, DJ Leeming, AC Bay-Jensen, MA Karsdal Nidogen-1 Degraded by Cathepsin S can be Quantified in Serum and is Associated with Non-Small Cell Lung Cancer Neoplasia, 2017-03-07;19(4):271-278. 2017-03-07 [PMID: 28282545] (Human)		Human

Array DY2570

• Nidogen-1/Entactin Antibodies
• Nidogen-1/Entactin Lysate
• Nidogen-1/Entactin Proteins and Enzyme
• Nidogen-1/Entactin ELISA