Human Granulysin DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Granulysin, formerly known as NKG5 or Lymphokine LAG-2, is a membrane-lytic protein that is expressed in granules of natural killer and activated cytotoxic T cells. It exhibits cytolytic activity against intracellular or extracellular microbes and also tumors, either alone or in synergy with Perforin. IL-15 is necessary and sufficient for Granulysin release from CD8+ T cells. Granulysin promotes chemotaxis and increases production of chemokines by monocytic cells as well as target cell lysis. It binds and disrupts microbial membranes through charge interactions.

We have publications tested in 2 confirmed species: Human, Mouse.

Showing Publications 1 - 7 of 7.

Publications using DY3138	Applications	Species
Pandiarajan, AN;Kumar, NP;Rajamanickam, A;Bhavani, PK;Jeyadeepa, B;Selvaraj, N;Asokan, D;Tripathy, S;Padmapriyadarsini, C;Babu, S; Enhanced Antimicrobial Peptide Response Following Bacillus Calmette-Guerin Vaccination in Elderly Individuals Vaccines 2024-09-18 [PMID: 39340094] (Human)		Human
J Friebel, M Witkowski, M Wegner, L Blöbaum, S Lammel, PA Schencke, K Jakobs, M Puccini, D Rei beta ner, D Steffens, V Moos, HP Schutheiss, U Landmesser, U Rauch Cytotoxic CD8+ T Cells Are Involved in the Thrombo-Inflammatory Response during First-Diagnosed Atrial Fibrillation Cells, 2022-12-29;12(1):. 2022-12-29 [PMID: 36611934] (Human)		Human
H Jiang, CW Wang, Z Wang, Y Dai, Y Zhu, YS Lee, Y Cao, WH Chung, S Ouyang, H Wang Functional and structural characteristics of HLA-B*13:01-mediated specific T cells reaction in dapsone-induced drug hypersensitivity Journal of Biomedical Science, 2022-08-13;29(1):58. 2022-08-13 [PMID: 35964029] (Human)		Human
L Krabbendam, BA Heesters, CMA Kradolfer, NJE Haverkate, MAJ Becker, CJ Buskens, WA Bemelman, JH Bernink, H Spits CD127+ CD94+ innate lymphoid cells expressing granulysin and perforin are expanded in patients with Crohn's disease Nature Communications, 2021-10-06;12(1):5841. 2021-10-06 [PMID: 34615883] (Mouse)		Mouse
C Junqueira, RB Polidoro, G Castro, S Absalon, Z Liang, S Sen Santar, Â Crespo, DB Pereira, RT Gazzinelli, JD Dvorin, J Lieberman &gamma&delta T cells suppress Plasmodium falciparum blood-stage infection by direct killing and phagocytosis Nature Immunology, 2021-01-11;0(0):. 2021-01-11 [PMID: 33432229] (Human)		Human
C Junqueira, CRR Barbosa, PAC Costa, A Teixeira-C, G Castro, S Sen Santar, RP Barbosa, F Dotiwala, DB Pereira, LR Antonelli, J Lieberman, RT Gazzinelli Cytotoxic CD8+ T cells recognize and kill Plasmodium vivax-infected reticulocytes Nat. Med., 2018-07-23;0(0):. 2018-07-23 [PMID: 30038217] (Human)		Human
NP Kumar, K Moideen, V Viswanatha, S Sivakumar, PA Menon, H Kornfeld, S Babu Heightened circulating levels of antimicrobial peptides in tuberculosis-Diabetes co-morbidity and reversal upon treatment PLoS ONE, 2017-09-14;12(9):e0184753. 2017-09-14 [PMID: 28910369] (Human)		Human

Array DY3138

• Granulysin Antibodies
• Granulysin Lysate
• Granulysin Protein
• Granulysin Proteins and Enzyme
• Granulysin ELISA