Human ADAMTS4 DuoSet ELISA, 5 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Members of the ADAMTS family contain pro, catalytic, disintegrin-like, cysteine-rich, spacer and a variable number of TS type 1 motifs. In contrast to membrane-anchored ADAMs, ADAMTSs are secreted and are all active proteases. They are essential for aggrecan turnover and procollagen processing, regulation of which is important in many physiological and pathological processes such as angiogenesis and arthritis.

We have publications tested in 2 confirmed species: Human, Mouse.

Showing Publications 1 - 10 of 10.

Publications using DY4307-05	Applications	Species
W Zhang, BY Chua, KJ Selva, L Kedzierski, TM Ashhurst, ER Haycroft, SK Shoffner-B, L Hensen, DF Boyd, F James, E Mouhtouris, JC Kwong, KYL Chua, G Drewett, A Copaescu, JE Dobson, LC Rowntree, JR Habel, LF Allen, HF Koay, JA Neil, MJ Gartner, CY Lee, P Andersson, SF Khan, L Blakeway, J Wisniewski, JH McMahon, EE Vine, AL Cunningham, J Audsley, I Thevarajan, T Seemann, NL Sherry, F Amanat, F Krammer, SL Londrigan, LM Wakim, NJC King, DI Godfrey, LK Mackay, PG Thomas, S Nicholson, KB Arnold, AW Chung, NE Holmes, OC Smibert, JA Trubiano, CL Gordon, THO Nguyen, K Kedzierska SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity Nature Communications, 2022-05-19;13(1):2774. 2022-05-19 [PMID: 35589689] (Human)		Human
W Zhang, B Chua, K Selva, L Kedzierski, T Ashhurst, E Haycroft, S Shoffner, L Hensen, D Boyd, F James, E Mouhtouris, J Kwong, K Chua, G Drewett, A Copaescu, J Dobson, L Rowntree, J Habel, L Allen, HF Koay, J Neil, M Gartner, C Lee, P Andersson, T Seemann, N Sherry, F Amanat, F Krammer, S Londrigan, L Wakim, N King, D Godfrey, L Mackay, P Thomas, S Nicholson, K Arnold, A Chung, N Holmes, O Smibert, J Trubiano, C Gordon, T Nguyen, K Kedzierska Immune responses in COVID-19 respiratory tract and blood reveal mechanisms of disease severity Research square, 2021-08-26;0(0):. 2021-08-26 [PMID: 34462740] (Human)		Human
DF Boyd, EK Allen, AG Randolph, XJ Guo, Y Weng, CJ Sanders, R Bajrachary, NK Lee, CS Guy, P Vogel, W Guan, Y Li, X Liu, T Novak, MM Newhams, TP Fabrizio, N Wohlgemuth, PM Mourani, PALISI Ped, TN Wight, S Schultz-Ch, SA Cormier, K Shaw-Salib, A Pekosz, RE Rothman, KF Chen, Z Yang, RJ Webby, N Zhong, JC Crawford, PG Thomas Exuberant fibroblast activity compromises lung function via ADAMTS4 Nature, 2020-10-28;0(0):. 2020-10-28 [PMID: 33116313] (Mouse)		Mouse
J Cassuto, A Folestad, J Göthlin, H Malchau, J Kärrholm Concerted actions by MMPs, ADAMTS and serine proteases during remodeling of the cartilage callus into bone during osseointegration of hip implants Bone Rep, 2020-09-11;13(0):100715. 2020-09-11 [PMID: 32995386] (Human)		Human
Z Zhang, Z Zha, Z Zhao, W Liu, W Li Lentinan Inhibits AGE-Induced Inflammation and the Expression of Matrix-Degrading Enzymes in Human Chondrocytes Drug Des Devel Ther, 2020-07-17;14(0):2819-2829. 2020-07-17 [PMID: 32764881] (Human)		Human
R Liu, H Wu, H Song Knockdown of TRIM8 Attenuates IL-1beta-induced Inflammatory Response in Osteoarthritis Chondrocytes Through the Inactivation of NF-kappaB Pathway Cell Transplant, 2020-01-01;29(0):9636897209436. 2020-01-01 [PMID: 32757662] (Human)		Human
J Lee, CY Lee, JH Park, HH Seo, S Shin, BW Song, IK Kim, SW Kim, S Lee, JC Park, S Lim, KC Hwang Differentiation of adipose-derived stem cells into functional chondrocytes by a small molecule that induces Sox9 Exp. Mol. Med., 2020-04-21;0(0):. 2020-04-21 [PMID: 32313200] (Human)		Human
MH Hwang, HG Son, JW Lee, CM Yoo, JH Shin, HG Nam, HJ Lim, SM Baek, JH Park, JH Kim, H Choi Photobiomodulation of extracellular matrix enzymes in human nucleus pulposus cells as a potential treatment for intervertebral disk degeneration Sci Rep, 2018-08-03;8(1):11654. 2018-08-03 [PMID: 30076336] (Human)		Human
J Chen, Y Luo, Y Zhou, S Qin, Y Qiu, R Cui, M Yu, J Qin, M Zhong Promotion of Tumor Growth by ADAMTS4 in Colorectal Cancer: Focused on Macrophages Cell. Physiol. Biochem., 2018-04-20;46(4):1693-1703. 2018-04-20 [PMID: 29694979] (Human, Mouse)		Human, Mouse
S Wang, Y Lu, Q Hong, X Geng, X Wang, W Zheng, C Song, C Liu, M Fan, Y Xi, M Guo, D Wu Protein Array-Based Detection of Proteins in Kidney Tissues from Patients with Membranous Nephropathy Biomed Res Int, 2017-02-27;2017(0):7843584. 2017-02-27 [PMID: 28337458] (Human)		Human

Array DY4307-05

• ADAMTS4 Antibodies
• ADAMTS4 ELISA Kits
• ADAMTS4 Lysate
• ADAMTS4 Proteins
• ADAMTS4 ELISA
• ADAMTS4 Proteins and Enzyme