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HM74A/PUMA-G/GPR109A/NIACR1 Antibody (245106) [DyLight 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
245106
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 488

Order Details

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HM74A/PUMA-G/GPR109A/NIACR1 Antibody (245106) [DyLight 488] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human HM74A/GPR109A
Met1-Pro363
Accession # Q8TDS4
Specificity
Detects human HM74A/GPR109A. Stains human HM74A/GPR109A-transfected cells but not irrelevant transfectants. Cross-reactivity with HM74 (GPR109B) was not tested.
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
HCAR2
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for HM74A/PUMA-G/GPR109A/NIACR1 Antibody (245106) [DyLight 488]

  • GPR109A
  • HCA2
  • HCAR2
  • HM74A
  • hydroxycarboxylic acid receptor 2
  • Niacr1
  • Nicotinic Acid Receptor
  • PUMAG

Background

Nicotinic acid receptors are a group of Gi/Go protein-coupled receptors that are currently divided into GPR81, GPR109Aand GPR109B subtypes. GPR109B receptors originated from a gene duplication of GPR109A and have > 95% homology. Allsubtypes are widely expressed throughout adipose tissue and are found at lower levels on macrophages, neutrophils,Langerhans cells and in the spleen. Nicotinic acid receptors are involved in the inhibition of lipolysis. The humangenes encoding these receptors are located on chromosome 12 (12q24.3)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol HCAR2