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HJURP Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: HJURP Antibody [NBP1-85025] - Staining of human cell line A-431 shows positivity in nucleus & nucleoli. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: HJURP Antibody [NBP1-85025] - Staining of human testis shows moderate to strong nuclear positivity in some spermatogonia cells.
Immunohistochemistry-Paraffin: HJURP Antibody [NBP1-85025] - Staining of human lymph node shows moderate to strong nuclear positivity in lymphoid cells.
Immunohistochemistry-Paraffin: HJURP Antibody [NBP1-85025] - Staining of human skin shows moderate nuclear positivity in a subset of basal cells in squamous epithelium.
Immunohistochemistry-Paraffin: HJURP Antibody [NBP1-85025] - Staining of human stomach shows moderate nuclear positivity in lymphoid cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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HJURP Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: TPVVQMATLTYETPQGLRIWGGRLIKERNEGEIQDSSMKPADRTDGSVQAAAWGPELPSHRTVLGADSKSGEVDATSDQEESVAWALAPAVPQSPLKNELRRKYLTQVDILLQGAEYFECAGNRAGRDVRV
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HJURP
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: PFA/Triton X-100
Control Peptide
HJURP Protein (NBP1-85025PEP)
Publications
Read Publications using NBP1-85025.

Reactivity Notes

Reactivity reported in scientific literature (PMID: 24039914)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for HJURP Antibody

  • FAKTS14-3-3-associated AKT substrate
  • fetal liver expressing gene 1
  • Fetal liver-expressing gene 1 protein
  • FLEG1
  • hFLEG1
  • Holliday junction recognition protein
  • Up-regulated in lung cancer 9
  • URLC9DKFZp762E1312

Background

Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Directly binds Holliday junctions

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for HJURP Antibody (NBP1-85025)(3)

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Bioinformatics

Gene Symbol HJURP