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Histone H2B [ac Lys11] Antibody (RM456) [Janelia Fluor® 669]

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Product Details

Summary
Reactivity Hu, VbSpecies Glossary
Applications WB, ELISA, Func
Clone
RM456
Clonality
Monoclonal
Host
Rabbit
Conjugate
Janelia Fluor 669

Order Details

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Histone H2B [ac Lys11] Antibody (RM456) [Janelia Fluor® 669] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
An acetyl-peptide corresponding to Histone H2B [Lys11] (Uniprot # P62807)
Modification
ac Lys11
Specificity
This antibody reacts to Histone H2B acetylated at Lysine 11. No cross reactivity with other acetylated Lysines in histones.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
H2BC18
Purity
Protein A purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Multiplex Immunoassay
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Histone H2B [ac Lys11] Antibody (RM456) [Janelia Fluor® 669]

  • FLJ35099
  • FLJ56780
  • FLJ56787
  • HIST1H2BK
  • histone 2, H2bf
  • histone cluster 2, H2bf
  • histone H2B type 2-F
  • Histone H2B
  • MGC131639

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility tothe cellular machineries which require DNA as a template. Histones thereby play a central role in transcriptionregulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set ofpost-translational modifications of histones, also called histone code, and nucleosome remodeling

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol H2BC18