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Histone H2B [ac Lys11] Antibody (RM456) - Azide and BSA Free

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Multiplex Immunoassay: Histone H2B [ac Lys11] Antibody (RM456) - Azide and BSA Free [NBP3-26035] - RM456 specifically reacts to Histone H2B acetylated at Lysine 11 (K11ac). No cross reactivity with non-modified Lysine ...read more
Western Blot: Histone H2B [ac Lys11] Antibody (RM456) - Azide and BSA Free [NBP3-26035] - Western Blot of acid extracts of HeLa cells treated (+) or untreated (-) with sodium butyrate, using Clone RM456 at 0.002 ug/mL.

Product Details

Summary
Reactivity Hu, VbSpecies Glossary
Applications WB, ELISA, Func
Clone
RM456
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
1 mg/ml

Order Details

Histone H2B [ac Lys11] Antibody (RM456) - Azide and BSA Free Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
An acetyl-peptide corresponding to Histone H2B [Lys11] (Uniprot # P62807)
Modification
ac Lys11
Specificity
This antibody reacts to Histone H2B acetylated at Lysine 11. No cross reactivity with other acetylated Lysines in histones.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
H2BC18
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 0.2 ug/mL - 1 ug/mL
  • Multiplex Immunoassay 0.01 ug/mL - 1 ug/mL
  • Western Blot 0.001 ug/mL - 0.01 ug/mL

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for Histone H2B [ac Lys11] Antibody (RM456) - Azide and BSA Free

  • FLJ35099
  • FLJ56780
  • FLJ56787
  • HIST1H2BK
  • histone 2, H2bf
  • histone cluster 2, H2bf
  • histone H2B type 2-F
  • Histone H2B
  • MGC131639

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility tothe cellular machineries which require DNA as a template. Histones thereby play a central role in transcriptionregulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set ofpost-translational modifications of histones, also called histone code, and nucleosome remodeling

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol H2BC18