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Histone H2B [ubiquitylated Lys123] Antibody (1B3F12/A9) [DyLight 405]

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Product Details

Summary
Reactivity Hu, Y, YeSpecies Glossary
Applications WB, ELISA, ICC/IF, ChIP
Clone
1B3F12/A9
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

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Histone H2B [ubiquitylated Lys123] Antibody (1B3F12/A9) [DyLight 405] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Clone formerly called "H2BK123"
Immunogen
Ub-polypeptide antigen based on amino acids 115 - 130 of yeast Histone H2B
Modification
ubiquitylated Lys123
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
H2BC18
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Chromatin Immunoprecipitation (ChIP)
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Saccharomyces cerevisiae

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Histone H2B [ubiquitylated Lys123] Antibody (1B3F12/A9) [DyLight 405]

  • FLJ35099
  • FLJ56780
  • FLJ56787
  • HIST1H2BK
  • histone 2, H2bf
  • histone cluster 2, H2bf
  • histone H2B type 2-F
  • Histone H2B
  • MGC131639

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility tothe cellular machineries which require DNA as a template. Histones thereby play a central role in transcriptionregulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set ofpost-translational modifications of histones, also called histone code, and nucleosome remodeling

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol H2BC18