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HIST3H3 Antibody (2128A) [mFluor Violet 500 SE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, Flow, ICC/IF
Clone
2128A
Clonality
Monoclonal
Host
Rabbit
Conjugate
mFluor Violet 500 SE

Order Details

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HIST3H3 Antibody (2128A) [mFluor Violet 500 SE] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Human HIST3H3 synthetic peptide
Specificity
Detects human HIST3H3 in Western blots.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry
  • Immunohistochemistry
  • Intracellular Staining by Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for HIST3H3 Antibody (2128A) [mFluor Violet 500 SE]

  • H3 histone family, member T
  • H3.4
  • H3/G
  • H3/gH3.4
  • H3/T
  • H3FT
  • H3FTMGC126888
  • H3t
  • H3tMGC126886
  • HIST3H3
  • Histone 3, H3
  • histone cluster 3, H3
  • histone H3.1t

Background

Histones are nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber as they play a critical role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. The HIST3H3 gene is intronless and encodes a 136 amino acid long, 15 kDA histone H3.1t protein that lacks polyA tails and obtain a palindromic termination element. The HIST3H3 gene is located separately from the other H3 genes on the cluster on chromosome 6p22-p21.3. HIST3H3 participates in PKA signaling, development notch signaling pathway, histone modification, and interferon pathway through interactions with genes HIST1H4B, HIST4H4, HIST1H4A, HIST1H4C, and HIST1H4D. HIST3H3 has been researched regarding its role in immunodeficiency, leukemia, prostatitis, huntington's disease, lupus, multiple sclerosis, laryngeal cancer, and lymphomas.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for HIST3H3 Antibody (FAB9448MFV500) (0)

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Secondary Antibodies

 

Isotype Controls

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Array FAB9448MFV500

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