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HIST1H2BA Antibody (OTI1C9) [Janelia Fluor® 585]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clone
OTI1C9
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 585

Order Details

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HIST1H2BA Antibody (OTI1C9) [Janelia Fluor® 585] Summary

Immunogen
Human recombinant protein fragment corresponding to amino acids 2-127 of human HIST1H2BA(NP_733759) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
HIST1H2BA
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for HIST1H2BA Antibody (OTI1C9) [Janelia Fluor® 585]

  • histone H2B type 1-A
  • bA317E16.3
  • H2BFU
  • histone cluster 1, H2ba
  • STBP
  • TSH2B

Background

HIST1H2BA is 127 amino acids long, weighs approximately 14 kDa, and the gene codes for a part of a group of basic nuclear proteins called histones, which are responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Current studies are being done on several diseases and disorders including systemic lupus erythematosus, lupus erythematosus, papillary adenoma, adenoma, and immunodeficiency. HIST1H2BA has also been shown to have interactions with BRD7, DNTTIP2, HIST2H2AC, SET, and CCNA1 in pathways such as the telomere maintenance, nucleosome assembly, cell cycle, FOXM1 transcription factor, and systemic lupus erythematosus pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol HIST1H2BA