HIST1H2BA Antibody (OTI1C9) [Janelia Fluor® 525] Summary
Immunogen |
Human recombinant protein fragment corresponding to amino acids 2-127 of human HIST1H2BA(NP_733759) produced in E.coli. |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
HIST1H2BA |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry
- Western Blot
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Reactivity Notes
Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Immunogen affinity purified |
Notes
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
Alternate Names for HIST1H2BA Antibody (OTI1C9) [Janelia Fluor® 525]
Background
HIST1H2BA is 127 amino acids long, weighs approximately 14 kDa, and the gene codes for a part of a group of basic nuclear proteins called histones, which are responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Current studies are being done on several diseases and disorders including systemic lupus erythematosus, lupus erythematosus, papillary adenoma, adenoma, and immunodeficiency. HIST1H2BA has also been shown to have interactions with BRD7, DNTTIP2, HIST2H2AC, SET, and CCNA1 in pathways such as the telomere maintenance, nucleosome assembly, cell cycle, FOXM1 transcription factor, and systemic lupus erythematosus pathways.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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