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Hemoglobin A2 Antibody (rHBA/9167) [FITC]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
rHBA/9167
Clonality
Monoclonal
Host
Mouse
Conjugate
FITC

Order Details

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Hemoglobin A2 Antibody (rHBA/9167) [FITC] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Recombinant fragment (around aa1-100) of human Hemoglobin A2 protein (exact sequence is proprietary)
Localization
Extracellular space.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
HBA2
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for Hemoglobin A2 Antibody (rHBA/9167) [FITC]

  • alpha globin
  • alpha-2 globin
  • alpha-globin
  • Hemoglobin alpha chain
  • hemoglobin subunit alpha
  • hemoglobin, alpha 2

Background

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta -pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) codingsequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but theydiffer significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA,which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains toconstitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemiasresult from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alphathalassemias have also been reported. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol HBA2