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HDAC3 Antibody (RM439)

Images

 
Immunohistochemistry-Paraffin: HDAC3 Antibody (RM439) [NBP3-23463] - Immunohistochemical staining of formalin fixed and paraffin embedded human brain cancer tissue sections using Clone RM439) at 1:200 dilution.
Western Blot: HDAC3 Antibody (RM439) [NBP3-23463] - Western Blot of Jurkat cell lysate using Clone RM439) at 1:1000 dilution.
Immunohistochemistry-Paraffin: HDAC3 Antibody (RM439) [NBP3-23463] - Immunohistochemical staining of formalin fixed and paraffin embedded human lung squamous carcinoma tissue sections using Clone RM439) at 1:200 ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
RM439
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

HDAC3 Antibody (RM439) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A peptide corresponding to the C-terminus of HDAC3 (Uniprot#: O15379)
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
HDAC3
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:100 - 1:200
  • Western Blot 1:1000 - 1:2000

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
50% Glycerol/PBS, 1% BSA
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Notes

[Public Notes]

Alternate Names for HDAC3 Antibody (RM439)

  • EC 3.5.1.98
  • HD3RPD3-2RPD3
  • HDAC3
  • Histone Deacetylase 3
  • KDAC3
  • RPD3-2
  • SMAP45

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone cetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone acetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol HDAC3