HDAC3 Antibody (RM439) Summary
Additional Information |
Recombinant Monoclonal Antibody |
Immunogen |
A peptide corresponding to the C-terminus of HDAC3 (Uniprot#: O15379) |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
HDAC3 |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry 1:100 - 1:200
- Western Blot 1:1000 - 1:2000
|
Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
50% Glycerol/PBS, 1% BSA |
Preservative |
0.09% Sodium Azide |
Purity |
Protein A purified |
Notes
Alternate Names for HDAC3 Antibody (RM439)
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone cetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone acetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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