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HCN3 Antibody

Images

 
Immunohistochemistry-Paraffin: HCN3 Antibody [NBP1-81402] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry: HCN3 Antibody [NBP1-81402] - Staining of human duodenum shows strong cytoplasmic and membranous positivity in glandular cells.
Immunohistochemistry-Paraffin: HCN3 Antibody [NBP1-81402] - Staining of human duodenum shows strong membranous positivity in glandular cells.
Immunohistochemistry-Paraffin: HCN3 Antibody [NBP1-81402] - Staining of human kidney shows weak cytoplasmic positivity in cells in tubules.
Immunohistochemistry-Paraffin: HCN3 Antibody [NBP1-81402] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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HCN3 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: LPLSPDSPATLLARSAWRSAGSPASPLVPVRAGPWASTSRLPAPPARTLHASLSRAGRSQVSLLGPPPGGGGRRLGPRGRPLSASQPSLPQRATGDGSPGRKGSGSERLPPSGLLAKPPRTAQPPRPPVPEPATPRGLQLS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HCN3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
HCN3 Protein (NBP1-81402PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (88%), Rat (88%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for HCN3 Antibody

  • HCN3
  • hyperpolarization activated cyclic nucleotide-gated potassium channel 3
  • KIAA1535
  • KIAA1535MGC131493
  • potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3

Background

FUNCTION: Putative hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. SUBUNIT: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming subunits. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. DOMAIN: The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional HCN3 Products

Array NBP1-81402

Research Areas for HCN3 Antibody (NBP1-81402)

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Blogs on HCN3

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Bioinformatics

Gene Symbol HCN3