Human Growth Hormone R ELISA Kit (Colorimetric) Summary
Specificity |
This kit recognizes Human GHR in samples. No significant cross-reactivity or interference between Human GHR and analogues was observed. |
Standard Curve Range |
1.56 - 100 ng/mL |
Sensitivity |
0.94 ng/mL |
Assay Type |
Sandwich-ELISA |
Inter-Assay |
CV% < 4.71% |
Intra-Assay |
CV% < 5.47% |
Spike Recovery |
85-111% |
Sample Volume |
100 uL |
Kit Type |
ELISA Kit (Colorimetric) |
Gene |
GHR |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Storage of components varies. See protocol for specific instructions. |
Kit Components
Components
|
- Biotinylated Detection Ab Diluent
- Concentrated Biotinylated Detection Ab (100×)
- Concentrated HRP Conjugate (100×)
- Concentrated Wash Buffer (25×)
- HRP Conjugate Diluent
- Micro ELISA Plate(Dismountable)
- Plate Sealer
- Product Description
- Reference Standard & Sample Diluent
- Reference Standard
- Stop Solution
- Substrate Reagent
|
Alternate Names for Human Growth Hormone R ELISA Kit (Colorimetric)
Background
Growth hormone receptor encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are
guaranteed for 6 months from date of receipt.
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