Glutathione S-Transferase pi 1/GSTP1 Antibody

GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, which is located on chromosome 11q13 , is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90%) of prostate carcinomas and is associated with transcriptional down-regulation.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 applications: ICC/IF, WB.

Showing Publication 1 - 1 of 1.

Publication using NBP1-84748	Applications	Species
Pellacani D, Kestoras D, Droop AP et al. DNA hypermethylation in prostate cancer is a consequence of aberrant epithelial differentiation and hyperproliferation. Cell Death Differ 2014-05-01 [PMID: 24464224] (ICC/IF, WB)	ICC/IF, WB

Array NBP1-84748

• Glutathione S-Transferase pi 1/GSTP1 Antibodies
• Glutathione S-Transferase pi 1/GSTP1 ELISA Kits
• Glutathione S-Transferase pi 1/GSTP1 Lysate
• Glutathione S-Transferase pi 1/GSTP1 Proteins
• Glutathione S-Transferase pi 1/GSTP1 Proteins and Enzyme