Glutathione Peroxidase 4/GPX4 Antibody - Isoform a and c

Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using NB100-41379	Applications	Species
Su D, Novoselov SV, Sun QA et al. Mammalian selenoprotein thioredoxin/glutathione reductase: Roles in disulfide bond formation and sperm maturation. J Biol Chem 2005-05-18 [PMID: 15901730]

Array NB100-41379

• Glutathione Peroxidase 4/GPX4 Antibodies
• Glutathione Peroxidase 4/GPX4 ELISA Kits
• Glutathione Peroxidase 4/GPX4 Lysate
• Glutathione Peroxidase 4/GPX4 Proteins