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GABA-AR alpha 5 Antibody (S415-24) [DyLight 550]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
S415-24
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 550

GABA-AR alpha 5 Antibody (S415-24) [DyLight 550] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
Fusion protein amino acids 368-419 (last cytoplasmic domain before extracellular C-terminus) of human GABA A Receptor Alpha5.
Localization
Cell Junction , Synapse , Postsynaptic Cell Membrane , Cell Membrane
Specificity
Detects ~55kDa. Does not cross-react with GABA A Receptor Alpha2 or other GABA-A Receptors based on KO validation data.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
GABRA5
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for GABA-AR alpha 5 Antibody (S415-24) [DyLight 550]

  • GABA A R alpha 5
  • GABA(A) receptor subunit alpha-5
  • GABAAR alpha 5
  • GABAARa5
  • GABRA5
  • gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • gamma-aminobutyric acid receptor subunit alpha-5
  • MGC138184

Background

GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics. GABA (A) Receptors are comprised of subunits and these are further classified into 3 major groups (alpha, beta, and gamma). The subunits determine the pharmacological characteristics.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for GABA-AR alpha 5 Antibody (NBP2-59700R) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GABRA5