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FYB/ADAP/SLAP130 Antibody

Images

 
Immunohistochemistry-Paraffin: FYB/ADAP/SLAP130 Antibody [NBP1-91916] - Staining of human lymph node shows high expression.
Immunohistochemistry: FYB/ADAP/SLAP130 Antibody [NBP1-91916] - Staining of human tonsil shows strong cytoplasmic positivity.
Immunohistochemistry-Paraffin: FYB/ADAP/SLAP130 Antibody [NBP1-91916] - Staining of human cerebral cortex shows low expression as expected.
Orthogonal Strategies: Immunohistochemistry-Paraffin: FYB/ADAP/SLAP130 Antibody [NBP1-91916] - Staining in human lymph node and cerebral cortex tissues using anti-FYB antibody. Corresponding FYB RNA-seq data are ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

FYB/ADAP/SLAP130 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: RPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQD
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FYB1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
FYB/ADAP/SLAP130 Protein (NBP1-91916PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for FYB/ADAP/SLAP130 Antibody

  • ADAP
  • Adhesion and degranulation promoting adaptor protein
  • adhesion and degranulation-promoting adaptor protein
  • FYB
  • FYB-120/130SLAP-130FYN-binding protein (FYB-120/130)
  • FYN binding protein
  • FYN-binding protein
  • FYN-T-binding protein
  • p120/p130
  • PRO0823
  • SLAP130
  • SLP-76-associated phosphoprotein

Background

FYB acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression ofinterleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol FYB1