Novus Biologicals products are now on bio-techne.com

FXYD2 Antibody [Janelia Fluor® 646]

Images

 
There are currently no images for FXYD2 Antibody (NBP2-97415JF646).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 646

Order Details

Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

FXYD2 Antibody [Janelia Fluor® 646] Summary

Immunogen
Produced in rabbits immunized with E. coli-derived Human FXYD2 fragment.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FXYD2
Purity
Antigen and protein A Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for FXYD2 Antibody [Janelia Fluor® 646]

  • ATP1C
  • ATP1G1
  • ATP1G1ATPase, Na+/K+ transporting, gamma 1 polypeptide
  • FXYD domain containing ion transport regulator 2
  • FXYD domain-containing ion transport regulator 2
  • FXYD2
  • HOMG2
  • hypomagnesemia 2, renal
  • MGC12372
  • Na(+)/K(+) ATPase subunit gamma
  • Sodium pump gamma chain
  • sodium/potassium-transporting ATPase subunit gamma
  • Sodium-potassium-ATPase, gamma polypeptide

Background

FXYD2 encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The Type III integral membrane protein encoded by this gene is the gamma subunit of the Na,K-ATPase present on the plasma membrane. Although the Na,K-ATPase does not depend on the gamma subunit to be functional, it is thought that the gamma subunit modulates the enzyme's activity by inducing ion channel activity. Mutations in this gene have been associated with renal hypomagnesaemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-95165
Species: Mu, Rt
Applications: WB
NBP2-48725
Species: Hu
Applications: IHC, IHC-P, WB
H00010926-M01
Species: Hu
Applications: ELISA, ICC/IF, IHC, IHC-P, S-ELISA, WB
NBP1-89680
Species: Hu, Mu
Applications: ChIP, ICC/IF, IHC, IHC-P, Simple Western, WB
NBP2-81950
Species: Hu, Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-P, WB
NBP2-01991
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
NBP1-82486
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
AF4965
Species: Mu
Applications: IHC, Simple Western, WB
MAB7936
Species: Hu
Applications: CyTOF-ready, IHC, ICFlow
AF2254
Species: Mu
Applications: IHC, WB
AF3444
Species: Hu
Applications: IHC, WB
NBP2-52894
Species: Hu
Applications: IHC, IHC-P, WB
AF2396
Species: Hu
Applications: IHC, Simple Western, WB
AF8355
Species: Hu
Applications: IHC, WB
NB100-93304
Species: ChHa, Hu
Applications: IP, WB
AF2419
Species: Hu
Applications: Dual ISH-IHC, ICC, IHC, Simple Western, WB
NB100-1869
Species: Hu, Mu, Rt
Applications: ELISA, Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, WB
NBP1-49672
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-Fr, IHC-P, In vitro, Simple Western, WB
NBP2-19807
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
NBP2-97415JF646
Species: Hu
Applications: IHC

Publications for FXYD2 Antibody (NBP2-97415JF646) (0)

There are no publications for FXYD2 Antibody (NBP2-97415JF646).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for FXYD2 Antibody (NBP2-97415JF646) (0)

There are no reviews for FXYD2 Antibody (NBP2-97415JF646). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for FXYD2 Antibody (NBP2-97415JF646) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our FXYD2 Antibody [Janelia Fluor® 646] and receive a gift card or discount.

Bioinformatics

Gene Symbol FXYD2