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Frizzled-7 Antibody [Janelia Fluor® 549]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 549

Order Details

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Frizzled-7 Antibody [Janelia Fluor® 549] Summary

Immunogen
Reacts with residues 1-12 [MRGPGTAASHSPC] of mouse fz7. 91% identity rat.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FZD7
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Use in Human reported in scientific literature (PMID:34390652). Mouse.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Frizzled-7 Antibody [Janelia Fluor® 549]

  • frizzled (Drosophila) homolog 7
  • frizzled homolog 7 (Drosophila)
  • Frizzled, drosophila, homolog of, 7
  • Frizzled7
  • Frizzled-7
  • fz-7
  • FZD7
  • FzE3frizzled-7
  • hFz7

Background

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FZD7