Frizzled-7 Products

Description

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq]

Bioinformatics

Entrez	14369 Mouse 8324 Human
Uniprot	AAH15915.1 Human NM_003507 Human NP_003498 Human NP_003498.1 Human O75084 Human Q61090 Mouse
Product By Gene ID	8324
Alternate Names	frizzled (Drosophila) homolog 7 frizzled homolog 7 (Drosophila) Frizzled, drosophila, homolog of, 7 fz-7 Fz-7 FzE3frizzled-7 hFz7

Research Areas for Frizzled-7

Find related products by research area and learn more about each of the different research areas below.

GPCR
Growth and Development
Neuronal Cell Markers
Signal Transduction
Wnt Signaling Pathway