Frizzled-7 Antibody

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using NB100-93398	Applications	Species
Vincan E, Darcy PK, Farrelly CA et al. Frizzled-7 dictates three-dimensional organization of colorectal cancer cell carcinoids. Oncogene 2007-04-05 [PMID: 17016432]

Array NB100-93398

• Frizzled-7 Antibodies
• Frizzled-7 Protein
• Frizzled-7 Proteins and Enzymes