Ferroportin/SLC40A1 Antibody (1308C) [Alexa Fluor® 700] Summary
Additional Information |
Recombinant Monoclonal Antibody |
Immunogen |
Synthetic peptide containing human Ferroportin/SLC40A1 Accession # Q9NP59 |
Specificity |
Detects human Ferroportin/SLC40A1 in direct ELISAs. |
Source |
N/A |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Purity Statement |
Protein A or G purified from cell culture supernatant |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry 0.25-1 ug/10^6 cells
|
Packaging, Storage & Formulations
Storage |
Protect from light. Do not freeze.- 12 months from date of receipt, 2 to 8 °C as supplied.
|
Buffer |
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide. |
Notes
This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Ferroportin/SLC40A1 Antibody (1308C) [Alexa Fluor® 700]
Background
Ferroportin-1 (FPN1), also known as solute carrier family 40
member 1 (SLC40A1) or iron-regulated transporter 1 (IREG1), is a multi-pass
membrane protein that in humans is encoded by the SLC40A1 gene and is part of
the Ferroportin (Fpn) Family. Ferroportin 1 is an iron-regulated transporter
that is essential for iron homeostasis, playing a key role in intestinal iron
absorption, as well as cellular iron release and efflux. Ferroportin can be
regulated at many different levels including transcriptionally,
post-transcriptionally, through mRNA stability and post-translationally,
through protein turnover. Mutations affecting the SLC40A1 gene result in a
disorder of iron metabolism characterized by iron overload. Excess iron is
deposited in a variety of organs leading to their failure, and resulting in
serious illnesses including cirrhosis, hepatomas, diabetes, cardiomyopathy and
arthritis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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