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Fc gamma RIIIB/CD16b Antibody (24) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
24
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-12795AF350
Alexa Fluor 405
NBP3-12795AF405
Alexa Fluor 488
NBP3-12795AF488
Alexa Fluor 532
NBP3-12795AF532
Alexa Fluor 594
NBP3-12795AF594
Alexa Fluor 647
NBP3-12795AF647
Alexa Fluor 700
NBP3-12795AF700
Alexa Fluor 750
NBP3-12795AF750
Allophycocyanin
NBP3-12795APC
Biotin
NBP3-12795B
CoraFluor 1
NBP3-12795CL1
DyLight 350
NBP3-12795UV
DyLight 405
NBP3-12795V
DyLight 488
NBP3-12795G
DyLight 550
NBP3-12795R
DyLight 594
NBP3-12795DL594
DyLight 650
NBP3-12795C
DyLight 680
NBP3-12795FR
DyLight 755
NBP3-12795IR
FITC
NBP3-12795F
HRP
NBP3-12795H
Janelia Fluor 525
NBP3-12795JF525
Janelia Fluor 549
NBP3-12795JF549
Janelia Fluor 585
NBP3-12795JF585
Janelia Fluor 635
NBP3-12795JF635
Janelia Fluor 669
NBP3-12795JF669
PE
NBP3-12795PE
PerCP
NBP3-12795PCP
Unconjugated
NBP3-12795-100ul
mFluor Violet 450 SE
NBP3-12795MFV450
mFluor Violet 500 SE
NBP3-12795MFV500
mFluor Violet 610 SE
NBP3-12795MFV610
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Fc gamma RIIIB/CD16b Antibody (24) [Janelia Fluor® 646] Summary

Immunogen
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Fc gamma RIIIB/CD16b (Uniprot#: O75015.2; Met1-Ser200).
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
FCGR3B
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Fc gamma RIIIB/CD16b Antibody (24) [Janelia Fluor® 646]

  • CD16
  • CD16b antigen
  • CD16b
  • Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
  • Fc fragment of IgG, low affinity IIIb, receptor for (CD16)
  • Fc gamma RIIIB
  • FCG3
  • Fc-gamma receptor IIIb (CD 16)
  • Fc-gamma RIII
  • Fc-gamma RIIIb
  • Fc-gamma RIII-beta
  • FCGR3
  • FCGR3B
  • FcgRIIIB
  • FcR-10
  • fcRIII
  • FCRIIIB
  • IGFR3
  • IgG Fc receptor III-1
  • low affinity immunoglobulin gamma Fc region receptor III-B

Background

CD16 (FcgRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgRIII is expressed in two forms FcgRIII-A and -B. FcgRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FceRI-g subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgRIII-A is associated, moreover, with FceRI-b subunit. Besides IgG, FceRI-A can be triggered also by oligomeric IgE. FcgRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol FCGR3B