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ERR beta/NR3B2 Antibody [DyLight 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 350

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-81824AF350
Alexa Fluor 405
NBP2-81824AF405
Alexa Fluor 488
NBP2-81824AF488
Alexa Fluor 532
NBP2-81824AF532
Alexa Fluor 594
NBP2-81824AF594
Alexa Fluor 647
NBP2-81824AF647
Alexa Fluor 700
NBP2-81824AF700
Alexa Fluor 750
NBP2-81824AF750
Biotin
NBP2-81824B
CoraFluor 1
NBP2-81824CL1
DyLight 405
NBP2-81824V
DyLight 488
NBP2-81824G
DyLight 550
NBP2-81824R
DyLight 594
NBP2-81824DL594
DyLight 650
NBP2-81824C
DyLight 680
NBP2-81824FR
DyLight 755
NBP2-81824IR
FITC
NBP2-81824F
HRP
NBP2-81824H
Janelia Fluor 525
NBP2-81824JF525
Janelia Fluor 549
NBP2-81824JF549
Janelia Fluor 646
NBP2-81824JF646
Janelia Fluor 669
NBP2-81824JF669
PerCP
NBP2-81824PCP
Unconjugated
NBP2-81824
mFluor Violet 450 SE
NBP2-81824MFV450
mFluor Violet 500 SE
NBP2-81824MFV500
mFluor Violet 610 SE
NBP2-81824MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-81824
BSA Free
NBP2-81824
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ERR beta/NR3B2 Antibody [DyLight 350] Summary

Immunogen
ERR beta antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human ERR beta. The immunogen is located within amino acids 360 - 410 of ERR beta. Amino Acid Squence: LQDYELSQRHEEPWRTGKL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ESRRB
Purity
Peptide affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse: (89%), Rat: (89%)

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ERR beta/NR3B2 Antibody [DyLight 350]

  • ERR beta
  • ERR2
  • ESRL2
  • ESRRB
  • estrogen-related receptor beta
  • NR3B2

Background

Estrogen-related receptor beta (ERR beta) a NR3 Steroid Receptor, has been shown to affect early placental development. ERR beta also can act as a repressor of transcriptional activity mediated by the glucocorticoid receptor (GR). ERR beta binds as a monomer to the extended half-site TNAAGTGCA and as a homodimer to the estrogen response element (ERE), palindromic thyroid hormone response element (TRE(pal)), and SF-1 response element, but not to the glucocorticoid response element (GRE). ERR beta mutations lead to abnormal development of the chorion and defective diploid trophoblast proliferation, and are lethal during midgestation. ERR beta expression has been documented in mice in the extraembryonic ectoderm that gives rise to the chorion. ESTs have been isolated from normal human eye, lung, and testis libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ESRRB