eIF5A Antibody

EIF5A, previously known as EIF4D and IF-M2Ba, is a highly conserved 17-kDa protein that was originally characterized as a translation initiation factor, promoting the formation of the first peptide bond in mRNA translation in vitro. This is best positioned as a factor that controls the balance between cellular proliferation and death, depending upon the nature of cellular stress. Moreover, mutational analysis using human EIF5A to complement an EIF5A null strain of S. cerevisiae supports a role for EIF5A in protein synthesis. The activity of EIF5A is modulated by the covalent addition of the spermidine derivative hypusine to lysine residue 50.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 2 of 2.

Publications using NBP1-51982	Applications	Species
Gao Y, Mao Y, Miao Z. Enantioselective 1,3-Dipolar (5+3) Cycloadditions of Oxidopyrylium Ylides and Vinylcyclopropanes toward 9-Oxabicyclononanes. Organic letters 2022-04-29 [PMID: 35420826]
Koettnitz K, Kappel B, Baumruker T et al. The genomic structure encoding human initiation factor eIF-5A Gene 1994-01-01 [PMID: 7545941]

Array NBP1-51982

• eIF5A Antibodies
• eIF5A Lysates
• eIF5A Proteins