Dystonin Antibody (H5E.Hy.4B) Summary
Immunogen |
Bullous Pemphigoid Antigen was used as immunogen. |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Human |
Gene |
DST |
Purity |
Ion exchange chromatography |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/ Immunofluorescence 1:10-1:500
- Immunohistochemistry 1:10-1:500
- Immunohistochemistry-Frozen 1:10-1:500
- Western Blot 1:100-1:2000
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Publications |
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Reactivity Notes
Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
Tris-NaCl (pH 8.0) |
Preservative |
No Preservative |
Concentration |
0.5 mg/ml |
Purity |
Ion exchange chromatography |
Notes
This product is manufactured by Eurobio Scientific (formerly Dendritics) and distributed by Novus Biologicals.
Alternate Names for Dystonin Antibody (H5E.Hy.4B)
Background
Dystonin encodes a member of the plakin protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been known that some isoforms are expressed in neural and muscle tissue, anchoring neural intermediate filaments to the actin cytoskeleton, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing intermediate filaments to hemidesmosomes. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for Dystonin Antibody (DDX0450P-100)(1)
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