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DNAM-1/CD226 Antibody (838216) [DyLight 755]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
838216
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 755

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB4436U-100UG
Alexa Fluor 405
FAB4436V-100UG
Alexa Fluor 488
FAB4436G-100UG
Alexa Fluor 532
FAB4436X
Alexa Fluor 594
FAB4436T-100UG
Alexa Fluor 647
FAB4436R-100UG
Alexa Fluor 700
FAB4436N-100UG
Alexa Fluor 750
FAB4436S-100UG
Allophycocyanin/Cy7
FAB4436APCCY7
Biotin
FAB4436B
CoraFluor 1
FAB4436CL1
DyLight 350
FAB4436D
DyLight 405
FAB4436E
DyLight 488
FAB4436K
DyLight 550
FAB4436L
DyLight 594
FAB4436M
DyLight 650
FAB4436W
DyLight 680
FAB4436Y
FITC
FAB4436F
HRP
FAB4436H
Janelia Fluor 525
FAB4436JF525
Janelia Fluor 549
FAB4436I
Janelia Fluor 585
FAB4436JF585
Janelia Fluor 635
FAB4436JF635
Janelia Fluor 646
FAB4436J
Janelia Fluor 669
FAB4436JF669
PE/Atto594
FAB4436PEATT594
PE/Cy5.5
FAB4436PECY55
PE/Cy7
FAB4436PECY7
PerCP
FAB4436C
Unconjugated
MAB4436
mFluor Violet 450 SE
FAB4436MFV450
mFluor Violet 500 SE
FAB4436MFV500
mFluor Violet 610 SE
FAB4436MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB4436
Carrier Free
MAB4436
Carrier Free
MAB4436-SP
Carrier Free
FAB4436V-100UG
Carrier Free
FAB4436U-100UG
Carrier Free
FAB4436T-100UG
Carrier Free
FAB4436S-100UG
Carrier Free
FAB4436R-100UG
Carrier Free
FAB4436N-100UG
Carrier Free
FAB4436G-100UG
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DNAM-1/CD226 Antibody (838216) [DyLight 755] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse DNAM-1/CD226
Met1-Pro254
Accession # Q8K4F0
Specificity
Detects mouse DNAM-1/CD226 in ELISAs. In direct ELISAs, no cross-reactivity with recombinant human DNAM-1/CD226 is observed.
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
CD226
Purity
Protein A or G purified from ascites
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from ascites

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for DNAM-1/CD226 Antibody (838216) [DyLight 755]

  • CD226 antigenplatelet and T cell activation antigen 1
  • CD226 molecule
  • CD226
  • DNAM1
  • DNAM-1
  • DNAM1adhesion glycoprotein
  • DNAM-1DNAX accessory molecule-1
  • DNAX accessory molecule 1
  • PTA1
  • T lineage-specific activation antigen 1 antigen
  • TLiSA1

Background

CD226 is a 65kD type I transmembrane glycoprotein, known as DNAM-1 (DNAX accessory molecule-1), PTA1(platelet and T cell activation antigen 1), or TLiSA1 (T lineage-specific activation antigen 1 antigen). It belongs to immunoglobulin superfamily containing 2 Ig-like domains, is expressed on majority of T lymphocytes, NK cells, monocytes, platelets, and a subset of B cells, activated endothelial cells. DNAM-1 is also expressed on CD8+ (but not CD8-) dendritic cells in mouse model. CD226 is an adhesion molecule involved in CTL and NK cell-mediated cytotoxicity. It has been identified that CD155 (poliovirus receptor, PVR) and CD112 (nectin-2, PRR-2) are CD226 ligands. DX11 antibody is able to inhibit CTL and NK cell-mediated cytotoxicity, and to block T cell cytokine production.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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DNAM-1/CD226
Antibody (838216) [Dy ...
FAB4436Z
DNAM-1/CD226 Antibody (838216) [DyLight 755]
Species: Mu
Applications: Flow, CyTOF-ready

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Bioinformatics

Gene Symbol CD226