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DNAM-1/CD226 Antibody (2770B) [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
2770B
Clonality
Monoclonal
Host
Rabbit
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB10988U-100UG
Alexa Fluor 405
FAB10988V-100UG
Alexa Fluor 488
FAB10988G-100UG
Alexa Fluor 532
FAB10988X
Alexa Fluor 594
FAB10988T-100UG
Alexa Fluor 647
FAB10988R-100UG
Alexa Fluor 700
FAB10988N-100UG
Alexa Fluor 750
FAB10988S-100UG
Allophycocyanin
FAB10988A
Allophycocyanin/Cy7
FAB10988APCCY7
CoraFluor 1
FAB10988CL1
DyLight 350
FAB10988D
DyLight 405
FAB10988E
DyLight 488
FAB10988K
DyLight 550
FAB10988L
DyLight 594
FAB10988M
DyLight 650
FAB10988W
DyLight 680
FAB10988Y
DyLight 755
FAB10988Z
FITC
FAB10988F
HRP
FAB10988H
Janelia Fluor 525
FAB10988JF525
Janelia Fluor 549
FAB10988I
Janelia Fluor 585
FAB10988JF585
Janelia Fluor 635
FAB10988JF635
Janelia Fluor 646
FAB10988J
Janelia Fluor 669
FAB10988JF669
PE
FAB10988P
PE/Atto594
FAB10988PEATT594
PE/Cy5.5
FAB10988PECY55
PE/Cy7
FAB10988PECY7
PerCP
FAB10988C
Unconjugated
MAB10988-100
mFluor Violet 450 SE
FAB10988MFV450
mFluor Violet 500 SE
FAB10988MFV500
mFluor Violet 610 SE
FAB10988MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB10988-100
Carrier Free
FAB10988T-100UG
Carrier Free
FAB10988R-100UG
Carrier Free
FAB10988G-100UG
Carrier Free
FAB10988S-100UG
Carrier Free
FAB10988N-100UG
Carrier Free
FAB10988U-100UG
Carrier Free
FAB10988V-100UG
Carrier Free
MAB10988-100
Carrier Free
MAB10988-SP
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DNAM-1/CD226 Antibody (2770B) [Biotin] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Human embryonic kidney cell HEK293-derived human DNAM-1/CD226 protein
Glu19-Asn247
Accession # Q15762
Specificity
Detects human DNAM-1/CD226 in direct ELISAs.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Purity
Protein A or G purified from cell culture supernatant
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from cell culture supernatant

Alternate Names for DNAM-1/CD226 Antibody (2770B) [Biotin]

  • CD226 antigenplatelet and T cell activation antigen 1
  • CD226 molecule
  • CD226
  • DNAM1
  • DNAM-1
  • DNAM1adhesion glycoprotein
  • DNAM-1DNAX accessory molecule-1
  • DNAX accessory molecule 1
  • PTA1
  • T lineage-specific activation antigen 1 antigen
  • TLiSA1

Background

CD226 is a 65kD type I transmembrane glycoprotein, known as DNAM-1 (DNAX accessory molecule-1), PTA1(platelet and T cell activation antigen 1), or TLiSA1 (T lineage-specific activation antigen 1 antigen). It belongs to immunoglobulin superfamily containing 2 Ig-like domains, is expressed on majority of T lymphocytes, NK cells, monocytes, platelets, and a subset of B cells, activated endothelial cells. DNAM-1 is also expressed on CD8+ (but not CD8-) dendritic cells in mouse model. CD226 is an adhesion molecule involved in CTL and NK cell-mediated cytotoxicity. It has been identified that CD155 (poliovirus receptor, PVR) and CD112 (nectin-2, PRR-2) are CD226 ligands. DX11 antibody is able to inhibit CTL and NK cell-mediated cytotoxicity, and to block T cell cytokine production.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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DNAM-1/CD226
Antibody (2770B) [Bio
FAB10988B
DNAM-1/CD226 Antibody (2770B) [Biotin]
Species: Hu
Applications: Flow

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