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Desmoglein-1 Antibody (32-2B) [DyLight 550]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
32-2B
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 550

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Desmoglein-1 Antibody (32-2B) [DyLight 550] Summary

Immunogen
Bovine desmoglein (desmosomal glyco protein I) from nasal epidermis. (Uniprot: Q02413)
Localization
Cell surface
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
DSG1
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Desmoglein-1 Antibody (32-2B) [DyLight 550]

  • Cadherin family member 4
  • CDHF4
  • CDHF4PPKS1
  • desmoglein 1
  • Desmoglein1
  • Desmoglein-1
  • Desmosomal glycoprotein 1
  • DG1
  • DGI
  • DSG
  • DSG1
  • Pemphigus foliaceus antigen
  • SPPK1

Background

Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. Desmoglein 1 has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol DSG1