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Derlin 1 Antibody [mFluor Violet 450 SE]

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Product Details

Summary
Reactivity Hu, Mu, Ca, ChHa, Rt, Bv, Ch, Xp, ZeSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
mFluor Violet 450 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-448AF350
Alexa Fluor 405
NB100-448AF405
Alexa Fluor 488
NB100-448AF488
Alexa Fluor 532
NB100-448AF532
Alexa Fluor 594
NB100-448AF594
Alexa Fluor 647
NB100-448AF647
Alexa Fluor 700
NB100-448AF700
Alexa Fluor 750
NB100-448AF750
Allophycocyanin
NB100-448APC
Biotin
NB100-448B
CoraFluor 1
NB100-448CL1
DyLight 350
NB100-448UV
DyLight 405
NB100-448V
DyLight 488
NB100-448G
DyLight 550
NB100-448R
DyLight 594
NB100-448DL594
DyLight 650
NB100-448C
DyLight 680
NB100-448FR
DyLight 755
NB100-448IR
FITC
NB100-448F
HRP
NB100-448H
Janelia Fluor 525
NB100-448JF525
Janelia Fluor 549
NB100-448JF549
Janelia Fluor 585
NB100-448JF585
Janelia Fluor 635
NB100-448JF635
Janelia Fluor 646
NB100-448JF646
Janelia Fluor 669
NB100-448JF669
PE
NB100-448PE
PerCP
NB100-448PCP
Unconjugated
NB100-448
mFluor Violet 500 SE
NB100-448MFV500
mFluor Violet 610 SE
NB100-448MFV610
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Derlin 1 Antibody [mFluor Violet 450 SE] Summary

Immunogen
A synthetic peptide made to the C-terminal region of human Derlin 1 (between residues 200-251). [UniProt# Q9BUN8]
Localization
Endoplasmic reticulum
Predicted Species
Rat (100%), Chicken (100%), Xenopus (100%), Bovine (100%), Zebrafish (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DERL1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Predicted to react with Xenopus, bovine, chicken, rat, zebrafish, and mouse based on 100% sequence homology. Mouse reactivity reported in scientific literature (PMID: 25377857)

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Derlin 1 Antibody [mFluor Violet 450 SE]

  • DER-1
  • DER1Degradation in endoplasmic reticulum protein 1
  • Der1-like domain family, member 1
  • Der1-like protein 1
  • derlin-1
  • DERtrin-1
  • FLJ13784
  • FLJ42092
  • MGC3067
  • PRO2577

Background

Degradation in Endoplasmic Reticulum protein 1 (Derlin1) is a channel-like protein, found in the ER membrane, responsible for degrading and funneling misfolded proteins and other cellular debris into the appropriate degradative pathways within the cell. Specifically, Derlin-1 is thought to form a channel to allow retrotranslocation of misfolded proteins into the cytosol where they may be ubiquitinated and degraded by the proteasome.

Derlin 1 antibodies will serve as useful tools for protein degradation studies and for research on certian types of cancers.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol DERL1