Delta Np73 Antibody (DNp73-1.1) - BSA Free Summary
Immunogen |
KLH-coupled synthetic peptide MLYVGDPARHLATC |
Epitope |
Target epitope is MLYVGDPARHLAT. |
Specificity |
The mouse monoclonal antibody DNp73-1.1 recognizes human Delta Np73. |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
TP73 |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry 1 ug/ml
- Immunocytochemistry/ Immunofluorescence
- Immunoprecipitation
- Western Blot 1-2 ug/ml
|
Application Notes |
Functional application: In human MOLT-4 T-cell line the antibody inhibits syncytium formation induced by coculture with human T-cell leukemia virus type 1 (HTLV-1)-positive human T-cell lines. Western blotting: positive control: Jurkat cells, non-reducing conditions. |
Packaging, Storage & Formulations
Storage |
Store at 4C. Do not freeze. |
Buffer |
PBS |
Preservative |
0.09% Sodium Azide |
Concentration |
1 mg/ml |
Purity |
Protein A purified |
Alternate Names for Delta Np73 Antibody (DNp73-1.1) - BSA Free
Background
The p53 family of proteins includes three members, p53, p63, and p73. The protein p73 is encoded by TP73 gene, which gives rise to protein isoforms with different properties and functions due to the presence (TAp73) or absence (deltaNp73) of an N-terminal transactivation domain. Investigations have been hampered by a lack of well characterized antibodies that are specific for p73 and do not cross-react with the related p53 and p63 proteins, as well as a lack of antibodies that specifically recognize either the TAp73 or deltaNp73 variants. We are introducing now such a set of antibodies.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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