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Delta Np73 Antibody (DNp73-1.1) - BSA Free

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Western Blot: Delta Np73 Antibody (DNp73-1.1) [NBP3-11702] - Analysis of p73 isoforms using mouse monoclonal antibody DNp73-1.1. This antibody is suitable for distinguishing between them. It detected specifically ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, ICC/IF, IP
Clone
DNp73-1.1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

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Delta Np73 Antibody (DNp73-1.1) - BSA Free Summary

Immunogen
KLH-coupled synthetic peptide MLYVGDPARHLATC
Epitope
Target epitope is MLYVGDPARHLAT.
Specificity
The mouse monoclonal antibody DNp73-1.1 recognizes human Delta Np73.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TP73
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1 ug/ml
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
  • Western Blot 1-2 ug/ml
Application Notes
Functional application: In human MOLT-4 T-cell line the antibody inhibits syncytium formation induced by coculture with human T-cell leukemia virus type 1 (HTLV-1)-positive human T-cell lines. Western blotting: positive control: Jurkat cells, non-reducing conditions.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS
Preservative
0.09% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for Delta Np73 Antibody (DNp73-1.1) - BSA Free

  • p53-related protein
  • p73
  • tumor protein p73

Background

The p53 family of proteins includes three members, p53, p63, and p73. The protein p73 is encoded by TP73 gene, which gives rise to protein isoforms with different properties and functions due to the presence (TAp73) or absence (deltaNp73) of an N-terminal transactivation domain. Investigations have been hampered by a lack of well characterized antibodies that are specific for p73 and do not cross-react with the related p53 and p63 proteins, as well as a lack of antibodies that specifically recognize either the TAp73 or deltaNp73 variants. We are introducing now such a set of antibodies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional Delta Np73 Products

Array NBP3-11702

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Bioinformatics

Gene Symbol TP73