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DCIR/CLEC4A Antibody (9E8) - Azide and BSA Free

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
9E8
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
1 mg/ml

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Azide and BSA Free
NBP3-09022-0.025mg
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DCIR/CLEC4A Antibody (9E8) - Azide and BSA Free Summary

Additional Information
Recombinant Monoclonal Antibody. Clone 9E8 was used by HLDA to establish CD designation.
Immunogen
This antibody was raised by immunising BALB/c mice with a dendritic cell immunoreceptor ectodomain-human Fc fusion protein.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CLEC4A
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
This antibody has been used in flow cytometric analysis of DCIR expression by peripheral blood mononuclear cells (Klechevsky et al, 2010). A recombinant humanised form of this antibody fused to protein antigens is under investigation as an antigen-targeting vaccine (Flamar et al, 2012), and has been shown to trigger antigen-specific CD8+ T cell immunity.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Proclin 300
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for DCIR/CLEC4A Antibody (9E8) - Azide and BSA Free

  • CD367
  • CLEC4A
  • CLECSF6
  • CLECSF6C-type lectin superfamily member 6
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 6
  • C-type lectin domain family 4 member A
  • C-type lectin domain family 4, member A
  • DCIR
  • DCIRLLIR
  • DDB27
  • DDB27C-type lectin DDB27
  • Dendritic cell immunoreceptor
  • Lectin-like immunoreceptor
  • LLIR

Background

CLEC4A, also known as DCIR, is a member of the C-type lectin/C-type lectin-like (CTL/CTLD) domain superfamily. Members of the CTL/CTLD family have a variety of functions including cell adhesion, glycoprotein turnover and cell-cell signaling. CLEC4A may play a role in regulating immune reactivity. This protein is currently being studied for research on the following diseases and disorders: rheumatoid arthritis, osteoarthritis, pneumonia, influenza, eclampsia and melanoma. CLEC4A is known to have interactions with PTPN6.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NBP3-09022
DCIR/CLEC4A Antibody (9E8) - Azide and BSA Free
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Bioinformatics

Gene Symbol CLEC4A