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DCIR/CLEC4A Antibody (216110)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clone
216110
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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DCIR/CLEC4A Antibody (216110) Summary

Additional Information
Clone 216110 was used by HLDA to establish CD designation
Immunogen
Mouse myeloma cell line NS0-derived recombinant human DCIR isoform 1
Gln70-Leu237
Accession # Q9UMR7
Specificity
Detects human DCIR in direct ELISAs and Western blots.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CLEC4A
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells
  • Western Blot 1 ug/mL
Publications
Read Publications using
MAB1748 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for DCIR/CLEC4A Antibody (216110)

  • CD367
  • CLEC4A
  • CLECSF6
  • CLECSF6C-type lectin superfamily member 6
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 6
  • C-type lectin domain family 4 member A
  • C-type lectin domain family 4, member A
  • DCIR
  • DCIRLLIR
  • DDB27
  • DDB27C-type lectin DDB27
  • Dendritic cell immunoreceptor
  • Lectin-like immunoreceptor
  • LLIR

Background

DCIR, also known as Lectin-like Immunoreceptor (LLIR), is a type II membrane protein belonging to the C-type lectin domain family and is designated CLEC4A (previously designated CLECSF6). Four transcript variants encoding distinct isoforms have been identified. DCIR contains one carbohydrate recognition domain in its C-terminal extracellular domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. Besides DC, DCIR is expressed on B cells, monocytes/macrophages and granulocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for DCIR/CLEC4A Antibody (MAB1748)(3)

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Bioinformatics

Gene Symbol CLEC4A
Uniprot