DAAM1 Antibody (4H3)

This product is produced by and distributed for Abnova, a company based in Taiwan.

Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein. Evidence of alternative splicing has been observed for this gene but the full-length nature of these variants has not been determined.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 2 applications: IP, WB.

Showing Publication 1 - 1 of 1.

Publication using H00023002-M03	Applications	Species
kawabata Galbraith k, Fujishima k, Mizuno H et al. MTSS1 Regulation of Actin-Nucleating Formin DAAM1 in Dendritic Filopodia Determines Final Dendritic Configuration of Purkinje Cells Cell Rep. 2018-07-03 [PMID: 29972794] (WB, IP, Mouse)	WB, IP	Mouse

Array H00023002-M03

• DAAM1 Antibodies
• DAAM1 Lysate
• DAAM1 Proteins