Cystathionase Antibody Summary
Immunogen |
Recombinant protein encompassing a sequence within the center region of human Cystathionase. The exact sequence is proprietary. |
Localization |
Cytoplasm |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
CTH |
Purity |
Antigen Affinity-purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry 1:100-1:1000
- Immunohistochemistry-Paraffin 1:100-1:1000
- Western Blot 1:500-1:3000
|
Theoretical MW |
45 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Publications |
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Reactivity Notes
Immunogen displays the following percentage of sequence identity for non-tested species: Porcine (86%), Bovine (89%).
Packaging, Storage & Formulations
Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
Buffer |
PBS (pH 7), 20% Glycerol |
Preservative |
0.025% Proclin 300 |
Purity |
Antigen Affinity-purified |
Alternate Names for Cystathionase Antibody
Background
This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for Cystathionase Antibody (NBP1-31759)(1)
Showing Publication 1 -
1 of 1.
Publication using NBP1-31759 |
Applications |
Species |
Md. Aejazur Rahman, Bridgette M. Cumming, Kelvin W. Addicott, Hayden T. Pacl, Shannon L. Russell, Kievershen Nargan, Threnesan Naidoo, Pratistadevi K. Ramdial, John H. Adamson, Rui Wang, Adrie J. C. Steyn Hydrogen sulfide dysregulates the immune response by suppressing central carbon metabolism to promote tuberculosis Proceedings of the National Academy of Sciences of the United States of America 2020-03-24 [PMID: 32139610] |
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Product General Protocols
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FAQs for Cystathionase Antibody (NBP1-31759) (0)
Secondary Antibodies
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