Reactivity | HuSpecies Glossary |
Applications | Flow, IHC, IP |
Clone | BNI3 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | PE |
Immunogen | Human CTLA-4/human IgG heavy chain fusion protein |
Specificity | NB100-64849 recognizes the human CD152 cell surface antigen, also known as CTLA-4 (cytotoxic T-lymphocyte-associated antigen 4). CD152 is a 45kD glycoprotein, expressed normally as a disulphide-linked homodimer. It is expressed transiently on the surface of T cells following activation (peaking at 3 days), but is often present with the cytoplasm. CD152 is a ligand for CD80 and CD86, and is important in cellular interactions during the immune response. |
Isotype | IgG2a |
Clonality | Monoclonal |
Host | Mouse |
Gene | CTLA4 |
Purity | Protein A or G purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Optimal dilution of this antibody should be experimentally determined. |
Storage | Store at 4C in the dark. |
Buffer | PBS |
Preservative | 0.05% Sodium Azide |
Purity | Protein A or G purified |
Secondary Antibodies |
Isotype Controls |
Research Areas for CTLA-4 Antibody (NB100-64849PE)Find related products by research area.
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CD86 - I work in tandem with CD80 CD86 belongs to the immunoglobulin superfamily of proteins that drive innate and adaptive immune responses. It is an 80kD co-stimulatory molecule for the priming and activation of naive and memory T-cells, respectively. CD86 is expressed on activated ... Read full blog post. |
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Gene Symbol | CTLA4 |