CRELD2 Antibody

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

CRELD2 is a ubiquitously expressed protein that is the second member of the CRELD family of matricellular proteins. Mouse CRELD2 is synthesized as a 350 amino acid precursor protein with a signal peptide, a highly conserved domain rich in glutamic acid and tryptophan (WE), and EGF-like repeats. Human CRELD2 has been shown to interact with the alpha 4 subunit of the nicotinic acetylcholine receptor and function as a specific regulator of receptor expression. Mouse CRELD2 shares 77% amino acid sequence homology with the human CRELD2 alpha isoform.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 2 applications: IHC, Western Blot.

Showing Publications 1 - 2 of 2.

Publications using AF3686	Applications	Species
KA Piróg, EP Dennis, CL Hartley, RM Jackson, J Soul, JM Schwartz, JF Bateman, RP Boot-Handf, MD Briggs XBP1 signalling is essential for alleviating mutant protein aggregation in ER-stress related skeletal disease PLoS Genet., 2019-07-01;15(7):e1008215. 2019-07-01 [PMID: 31260448] (IHC, Mouse)	IHC	Mouse
Y Kim, SJ Park, SR Manson, CA Molina, K Kidd, H Thiessen-P, RJ Perry, H Liapis, S Kmoch, CR Parikh, AJ Bleyer, YM Chen Elevated urinary CRELD2 is associated with endoplasmic reticulum stress-mediated kidney disease JCI Insight, 2017-12-07;2(23):. 2017-12-07 [PMID: 29212948] (Western Blot, Mouse)	Western Blot	Mouse

Array AF3686

• CRELD2 Antibodies
• CRELD2 Lysate
• CRELD2 Protein
• CRELD2 Proteins and Enzymes