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Complement Factor H-related 1/CFHR1/CFHL1 Antibody (442127)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clone
442127
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price
Carrier Free
MAB4247-SP
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Complement Factor H-related 1/CFHR1/CFHL1 Antibody (442127) Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Complement Factor H-related 1/CFHR1
Glu19-Ala328
Accession # Q03591
Specificity
Detects human Complement Factor H-related 1/CFHR1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with recombinant human (rh) CFHR2 or rhCFHR5 is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
CFHR1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • Immunoprecipitation 25 ug/mL
  • Western Blot 1 ug/mL
Publications
Read Publications using
MAB4247 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Complement Factor H-related 1/CFHR1/CFHL1 Antibody (442127)

  • BTA
  • CFHL1FHR-1
  • CFHLCFHR1P
  • CFHR1
  • complement factor H-related 1 pseudogene
  • Complement Factor Hrelated 1
  • Complement Factor H-related 1
  • complement factor H-related protein 1
  • FHR1
  • FHR1CFHL1P
  • H factor (complement)-like 1
  • H factor (complement)-like 2
  • H factor-like protein 1
  • H36-1
  • H36-2
  • H-factor-like 1
  • HFL1H36
  • HFL2
  • MGC104329

Background

Complement factor H-related protein 1 (CFHR1) is a 43 kDa, secreted member of the factor H family of glycoproteins. It is produced by hepatocytes and circulates as two differentially glycosylated isoforms (37 kDa and 43 kDa). Mature human CFHR1 is 312 aa in length. It contains five approximately 60 aa SCRs (short consensus repeats/CCPs/SUSHI repeats) that basically constitute the entire molecule. CFHR1 may play a role in lipoprotein complexes that bind LPS to neutrophils. There is no reported rodent counterpart to CFHR1. Over aa 19‑143 of the CFHR1 precursor, human CFHR2 and CFHR5 show 98% and 86% aa identity, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Complement Factor H-related 1/CFHR1/CFHL1 Antibody (MAB4247)(3)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Western Blot.


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Bioinformatics

Gene Symbol CFHR1
Uniprot