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Common gamma Chain/IL-2 R gamma Antibody (633162) [mFluor Violet 610 SE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, B/N, CyTOF-ready
Clone
633162
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 610 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB2842U-100UG
Alexa Fluor 405
FAB2842V-100UG
Alexa Fluor 488
FAB2842G-100UG
Alexa Fluor 532
FAB2842X
Alexa Fluor 594
FAB2842T-100UG
Alexa Fluor 647
FAB2842R-100UG
Alexa Fluor 700
FAB2842N-100UG
Alexa Fluor 750
FAB2842S-100UG
Allophycocyanin
FAB2842A
Allophycocyanin/Cy7
FAB2842APCCY7
Biotin
FAB2842B
CoraFluor 1
FAB2842CL1
DyLight 350
FAB2842D
DyLight 405
FAB2842E
DyLight 488
FAB2842K
DyLight 550
FAB2842L
DyLight 594
FAB2842M
DyLight 650
FAB2842W
DyLight 680
FAB2842Y
DyLight 755
FAB2842Z
HRP
FAB2842H
Janelia Fluor 525
FAB2842JF525
Janelia Fluor 549
FAB2842I
Janelia Fluor 646
FAB2842J
Janelia Fluor 669
FAB2842JF669
PE/Atto594
FAB2842PEATT594
PE/Cy5.5
FAB2842PECY55
PE/Cy7
FAB2842PECY7
PerCP
FAB2842C
Unconjugated
MAB2842
mFluor Violet 450 SE
FAB2842MFV450
mFluor Violet 500 SE
FAB2842MFV500
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB2842
Carrier Free
FAB2842A
Carrier Free
MAB2842
Carrier Free
MAB2842-SP
Carrier Free
FAB2842V-100UG
Carrier Free
FAB2842U-100UG
Carrier Free
FAB2842T-100UG
Carrier Free
FAB2842S-100UG
Carrier Free
FAB2842R-100UG
Carrier Free
FAB2842N-100UG
Carrier Free
FAB2842G-100UG
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Common gamma Chain/IL-2 R gamma Antibody (633162) [mFluor Violet 610 SE] Summary

Immunogen
S. frugiperda insect ovarian cell line Sf21-derived recombinant human Common gamma Chain/IL-2 gamma
Leu23-Asn254
Accession # P31785
Specificity
Detects human Common gamma Chain/IL-2 R gamma in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2 R alpha , rhIL-2 R beta , rhIL-15 R alpha , recombinant mouse IL-2 R gamma , or recombinant canine IL-2 R alpha is observed. In Western blots, approximately 80% cross-reactivity with recombinant human IL-2 R beta , 50% cross-reactivity with rhIL-15 R alpha and recombinant mouse IL-2 R alpha , and no cross-reactivity with rhIL-2 R alpha is observed.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
IL2RG
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Neutralization
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Common gamma Chain/IL-2 R gamma Antibody (633162) [mFluor Violet 610 SE]

  • CD132 antigen
  • CD132
  • CIDX
  • combined immunodeficiency, X-linked
  • common cytokine receptor gamma chain
  • Common gamma Chain
  • common gamma-chain
  • cytokine receptor common subunit gamma
  • gamma(c)
  • IL-2 R gamma
  • IL-2 receptor subunit gamma
  • IL2R gamma
  • IL-2R subunit gamma
  • IL2RG
  • IL-2RG
  • IMD4
  • interleukin 2 receptor, gamma
  • Interleukin-2 receptor subunit gamma
  • P64
  • SCIDX
  • SCIDX1
  • severe combined immunodeficiency

Background

The interleukin 2 (IL2) receptor gamma chain (IL2RG), an important signalling component of many interleukin receptors(IL2,IL4,IL7,IL9, and IL15), is thus referred to as the common gamma chain. Mutations in this X-chromosome-linked genecause X-linked severe combined immunodeficiency (XSCID). (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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As an alternative, please consider our next generation Recombinant Human IL-2 (BT-002). It has equivalent bioactivity to Recombinant Human IL-2 (Catalog # 202-IL). It combines R&D Systems quality with scalability that allows for a solid supply chain. Both Recombinant Human IL-2 proteins are measured in a cell proliferation assay using CTLL 2 mouse cytotoxic T cells.
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Bioinformatics

Gene Symbol IL2RG