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Common gamma Chain/IL-2 R gamma Antibody (633162) [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, B/N, CyTOF-ready
Clone
633162
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

Order Details

Common gamma Chain/IL-2 R gamma Antibody (633162) [DyLight 405] Summary

Immunogen
S. frugiperda insect ovarian cell line Sf21-derived recombinant human Common gamma Chain/IL-2 gamma
Leu23-Asn254
Accession # P31785
Specificity
Detects human Common gamma Chain/IL-2 R gamma in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2 R alpha , rhIL-2 R beta , rhIL-15 R alpha , recombinant mouse IL-2 R gamma , or recombinant canine IL-2 R alpha is observed. In Western blots, approximately 80% cross-reactivity with recombinant human IL-2 R beta , 50% cross-reactivity with rhIL-15 R alpha and recombinant mouse IL-2 R alpha , and no cross-reactivity with rhIL-2 R alpha is observed.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
IL2RG
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Neutralization
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Common gamma Chain/IL-2 R gamma Antibody (633162) [DyLight 405]

  • CD132 antigen
  • CD132
  • CIDX
  • combined immunodeficiency, X-linked
  • common cytokine receptor gamma chain
  • Common gamma Chain
  • common gamma-chain
  • cytokine receptor common subunit gamma
  • gamma(c)
  • IL-2 R gamma
  • IL-2 receptor subunit gamma
  • IL2R gamma
  • IL-2R subunit gamma
  • IL2RG
  • IL-2RG
  • IMD4
  • interleukin 2 receptor, gamma
  • Interleukin-2 receptor subunit gamma
  • P64
  • SCIDX
  • SCIDX1
  • severe combined immunodeficiency

Background

The interleukin 2 (IL2) receptor gamma chain (IL2RG), an important signalling component of many interleukin receptors(IL2,IL4,IL7,IL9, and IL15), is thus referred to as the common gamma chain. Mutations in this X-chromosome-linked genecause X-linked severe combined immunodeficiency (XSCID). (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol IL2RG