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Claudin-4 Antibody (382321) [Fluorescein]

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PC-3 human prostate cancer cell line was stained with Mouse Anti-Human Claudin-4 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB4219F, filled histogram) or isotype control antibody (Catalog # IC003F, open histogram). View our protocol for Staining Membrane-associated Proteins.
PC-3 human prostate cancer cell line was stained with Mouse Anti-Human Claudin-4 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB4219F, filled histogram) or isotype control antibody (Catalog # IC003F, open ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
382321
Clonality
Monoclonal
Host
Mouse
Conjugate
Fluorescein

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB4219U-100UG
Alexa Fluor 405
FAB4219V-100UG
Alexa Fluor 488
FAB4219G-100UG
Alexa Fluor 532
FAB4219X
Alexa Fluor 594
FAB4219T-100UG
Alexa Fluor 647
FAB4219R-100UG
Alexa Fluor 700
FAB4219N-100UG
Alexa Fluor 750
FAB4219S-100UG
Allophycocyanin
FAB4219A
Allophycocyanin/Cy7
FAB4219APCCY7
Biotin
FAB4219B
CoraFluor 1
FAB4219CL1
DyLight 350
FAB4219D
DyLight 405
FAB4219E
DyLight 488
FAB4219K
DyLight 550
FAB4219L
DyLight 594
FAB4219M
DyLight 650
FAB4219W
DyLight 680
FAB4219Y
DyLight 755
FAB4219Z
HRP
FAB4219H
Janelia Fluor 525
FAB4219JF525
Janelia Fluor 549
FAB4219I
Janelia Fluor 585
FAB4219JF585
Janelia Fluor 635
FAB4219JF635
Janelia Fluor 646
FAB4219J
Janelia Fluor 669
FAB4219JF669
PE/Atto594
FAB4219PEATT594
PE/Cy5.5
FAB4219PECY55
PE/Cy7
FAB4219PECY7
PerCP
FAB4219C
Phycoerythrin
FAB4219P
Unconjugated
MAB4219
mFluor Violet 450 SE
FAB4219MFV450
mFluor Violet 500 SE
FAB4219MFV500
mFluor Violet 610 SE
FAB4219MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB4219
Carrier Free
MAB4219
Carrier Free
FAB4219A
Carrier Free
FAB4219P
Carrier Free
MAB4219-SP
Carrier Free
FAB4219V-100UG
Carrier Free
FAB4219U-100UG
Carrier Free
FAB4219T-100UG
Carrier Free
FAB4219S-100UG
Carrier Free
FAB4219R-100UG
Carrier Free
FAB4219N-100UG
Carrier Free
FAB4219G-100UG
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Claudin-4 Antibody (382321) [Fluorescein] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human Claudin-4
Met1-Val209
Accession # NP_001296
Specificity
Detects human Claudin‑4. Stains human Claudin-4 transfectants but not irrelevant transfectants. Recognizes an epitope in the first extracellular loop (aa Met29-Arg81).
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CLDN4
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publication using
FAB4219F in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Claudin-4 Antibody (382321) [Fluorescein]

  • claudin 4
  • Claudin4
  • Claudin-4
  • CLDN4
  • Clostridium perfringens enterotoxin receptor 1
  • Clostridium perfringens enterotoxin receptor
  • CPE-R
  • CPE-RCPETR
  • CPE-receptor
  • CPETR1
  • hCPE-R
  • WBSCR8
  • WBSCR8CPERCPETR1claudin-4
  • Williams-Beuren syndrome chromosomal region 8 protein

Background

Claudin-4 is a multipass membrane protein in the claudin family of tight junction proteins. Claudin-4 is a 209 amino acid molecule with four transmembrane segments. It is preferentially expressed in intestinal mucosa epithelium and is involved in epithelial tissue development. It is also up-regulated in several carcinomas. Phosphorylation of Claudin-4 regulates paracellular epithelial permeability. Human Claudin-4 shares 83% aa sequence identity with mouse and rat Claudin-4.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Claudin-4 Antibody (FAB4219F)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Flow Cytometry.


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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CLDN4
Uniprot