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Claudin-4 Antibody (382321) [Allophycocyanin]

Images

 
PC-3 human prostate cancer cell line was stained with Mouse Anti-Human Claudin-4 APC-conjugated Monoclonal Antibody (Catalog # FAB4219A, filled histogram) or isotype control antibody (Catalog # IC003A, open histogram). ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
382321
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

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Claudin-4 Antibody (382321) [Allophycocyanin] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human Claudin-4
Met1-Val209
Accession # NP_001296
Specificity
Detects human Claudin‑4. Stains human Claudin-4 transfectants but not irrelevant transfectants. Recognizes an epitope in the first extracellular loop (aa Met29-Arg81).
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CLDN4
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Reviewed Applications
Read 1 Review rated 5
using
FAB4219A in the following application:

Publications
Read Publication using FAB4219A.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Claudin-4 Antibody (382321) [Allophycocyanin]

  • claudin 4
  • Claudin4
  • Claudin-4
  • CLDN4
  • Clostridium perfringens enterotoxin receptor 1
  • Clostridium perfringens enterotoxin receptor
  • CPE-R
  • CPE-RCPETR
  • CPE-receptor
  • CPETR1
  • hCPE-R
  • WBSCR8
  • WBSCR8CPERCPETR1claudin-4
  • Williams-Beuren syndrome chromosomal region 8 protein

Background

Claudin-4 is a multipass membrane protein in the claudin family of tight junction proteins. Claudin-4 is a 209 amino acid molecule with four transmembrane segments. It is preferentially expressed in intestinal mucosa epithelium and is involved in epithelial tissue development. It is also up‑regulated in several carcinomas. Phosphorylation of Claudin-4 regulates paracellular epithelial permeability. Human Claudin-4 shares 83% aa sequence identity with mouse and rat Claudin-4.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Claudin-4 Antibody (FAB4219A)(1)

Review for Claudin-4 Antibody (FAB4219A) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using FAB4219A:
Filter by Applications
Flow
(1)
All Applications
Filter by Species
Human
(1)
All Species
Images Ratings Applications Species Date Details
Flow Cytometry Claudin-4 FAB4219A
Enlarge
5
reviewed by:
Verified Customer
Flow Human 12/06/2016
View

Summary

ApplicationFlow Cytometry
Sample Tested293T cell line
SpeciesHuman
LotAAGV0110031

Product General Protocols

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FAQs for Claudin-4 Antibody (FAB4219A) (0)

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mFluor Violet Conjugated Antibodies

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Recent Reviews

5
5
1
4
0
3
0
2
0
1
0

Verified Customer
12/06/2016
Application: Flow
Species: Human

Bioinformatics

Gene Symbol CLDN4
Uniprot